Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes

Jennifer C Regan; Yu-Xuan Lu; Ekin Bolukbasi; Mobina Khericha; Linda Partridge

doi:10.1101/356295

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Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes

View ORCID ProfileJennifer C Regan, Yu-Xuan Lu, Ekin Bolukbasi, Mobina Khericha, Linda Partridge

doi: https://doi.org/10.1101/356295

Jennifer C Regan

1Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Gower St, London WC1E 6BT, UK

2Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany

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ORCID record for Jennifer C Regan

Yu-Xuan Lu

2Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany

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Ekin Bolukbasi

1Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Gower St, London WC1E 6BT, UK

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Mobina Khericha

1Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Gower St, London WC1E 6BT, UK

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Linda Partridge

1Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Gower St, London WC1E 6BT, UK

2Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany

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Posted June 26, 2018.

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Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes

Jennifer C Regan, Yu-Xuan Lu, Ekin Bolukbasi, Mobina Khericha, Linda Partridge

bioRxiv 356295; doi: https://doi.org/10.1101/356295

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Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes

Jennifer C Regan, Yu-Xuan Lu, Ekin Bolukbasi, Mobina Khericha, Linda Partridge

bioRxiv 356295; doi: https://doi.org/10.1101/356295

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