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Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes
Huan Wang, Robert P. Sheehan, Adam C. Palmer, Robert A. Everley, Sarah A. Boswell, Noga Ron-Harel, Kristina M. Holton, Connor A. Jacobson, Alison Erickson, Laura Maliszewski, Marcia C. Haigis, Peter K. Sorger
doi: https://doi.org/10.1101/365841
Huan Wang
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Robert P. Sheehan
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Adam C. Palmer
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Robert A. Everley
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
Sarah A. Boswell
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Noga Ron-Harel
3Department of Cell Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Kristina M. Holton
4Research Computing; Harvard Medical School; Boston, Massachusetts 02115, USA
Connor A. Jacobson
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
Alison Erickson
3Department of Cell Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Laura Maliszewski
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Marcia C. Haigis
3Department of Cell Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Peter K. Sorger
1Laboratory of Systems Pharmacology; Harvard Program in Therapeutic Science; Harvard Medical School; Boston, Massachusetts 02115, USA
2Department of Systems Biology; Harvard Medical School; Boston, Massachusetts 02115, USA
Posted July 30, 2018.
Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes
Huan Wang, Robert P. Sheehan, Adam C. Palmer, Robert A. Everley, Sarah A. Boswell, Noga Ron-Harel, Kristina M. Holton, Connor A. Jacobson, Alison Erickson, Laura Maliszewski, Marcia C. Haigis, Peter K. Sorger
bioRxiv 365841; doi: https://doi.org/10.1101/365841
Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes
Huan Wang, Robert P. Sheehan, Adam C. Palmer, Robert A. Everley, Sarah A. Boswell, Noga Ron-Harel, Kristina M. Holton, Connor A. Jacobson, Alison Erickson, Laura Maliszewski, Marcia C. Haigis, Peter K. Sorger
bioRxiv 365841; doi: https://doi.org/10.1101/365841
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