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C. elegans Mediator 15 permits low temperature-induced longevity via regulation of lipid and protein homeostasis

Dongyeop Lee, Seon Woo A. An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Dengke Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V. Lee
doi: https://doi.org/10.1101/366153
Dongyeop Lee
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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Seon Woo A. An
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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Yoonji Jung
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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Yasuyo Yamaoka
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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Youngjae Ryu
Research Division, Korea Brain Research Institute, Daegu, South Korea, 41068
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Grace Ying Shyen Goh
Centre for Molecular Medicine and Therapeutics, BC Children’s Hospital Research Institute, Department of Medical Genetics, University of British Columbia, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
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Arshia Beigi
Centre for Molecular Medicine and Therapeutics, BC Children’s Hospital Research Institute, Department of Medical Genetics, University of British Columbia, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
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Dengke Ma
Cardiovascular Research Institute and Department of Physiology, University of California San Francisco, San Francisco, CA, USA, 94158
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Chang Man Ha
Research Division, Korea Brain Research Institute, Daegu, South Korea, 41068
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Stefan Taubert
Centre for Molecular Medicine and Therapeutics, BC Children’s Hospital Research Institute, Department of Medical Genetics, University of British Columbia, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
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Youngsook Lee
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673Department of Integrative Bioscience & Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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Seung-Jae V. Lee
Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673School of Interdisciplinary Bioscience and Bioengineering, and Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
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  • For correspondence: seungjaelee@postech.ac.kr
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Article Information

doi 
https://doi.org/10.1101/366153
History 
  • July 10, 2018.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Dongyeop Lee1,
  2. Seon Woo A. An1,
  3. Yoonji Jung1,
  4. Yasuyo Yamaoka1,
  5. Youngjae Ryu4,
  6. Grace Ying Shyen Goh5,
  7. Arshia Beigi5,
  8. Dengke Ma6,
  9. Chang Man Ha4,
  10. Stefan Taubert5,
  11. Youngsook Lee1,3 and
  12. Seung-Jae V. Lee1,2,∗
  1. 1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
  2. 2School of Interdisciplinary Bioscience and Bioengineering, and Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
  3. 3Department of Integrative Bioscience & Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 37673
  4. 4Research Division, Korea Brain Research Institute, Daegu, South Korea, 41068
  5. 5Centre for Molecular Medicine and Therapeutics, BC Children’s Hospital Research Institute, Department of Medical Genetics, University of British Columbia, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
  6. 6Cardiovascular Research Institute and Department of Physiology, University of California San Francisco, San Francisco, CA, USA, 94158
  1. ↵∗Correspondence: seungjaelee{at}postech.ac.kr
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C. elegans Mediator 15 permits low temperature-induced longevity via regulation of lipid and protein homeostasis
Dongyeop Lee, Seon Woo A. An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Dengke Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V. Lee
bioRxiv 366153; doi: https://doi.org/10.1101/366153
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C. elegans Mediator 15 permits low temperature-induced longevity via regulation of lipid and protein homeostasis
Dongyeop Lee, Seon Woo A. An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Dengke Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V. Lee
bioRxiv 366153; doi: https://doi.org/10.1101/366153

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