New Results
CNTN5−/+ or EHMT2−/+ iPSC-Derived Neurons from Individuals with Autism Develop Hyperactive Neuronal Networks
Eric Deneault, Muhammad Faheem, Sean H. White, Deivid C. Rodrigues, Song Sun, Wei Wei, Alina Piekna, Tadeo Thompson, Jennifer L. Howe, Leon Chalil, Vickie Kwan, Susan Walker, Peter Pasceri, Frederick P. Roth, Ryan K.C. Yuen, Karun K. Singh, James Ellis, Stephen W. Scherer
doi: https://doi.org/10.1101/368928
Eric Deneault
1Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
Muhammad Faheem
1Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
Sean H. White
3Stem Cell and Cancer Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada;
Deivid C. Rodrigues
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
Song Sun
5Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada;
6The Donnelly Centre, University of Toronto, Toronto, ON, Canada;
8Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada;
Wei Wei
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
Alina Piekna
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
Tadeo Thompson
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
Jennifer L. Howe
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
Leon Chalil
3Stem Cell and Cancer Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada;
Vickie Kwan
3Stem Cell and Cancer Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada;
Susan Walker
1Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
Peter Pasceri
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
Frederick P. Roth
5Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada;
6The Donnelly Centre, University of Toronto, Toronto, ON, Canada;
7Department of Computer Science, University of Toronto, Toronto, ON, Canada;
8Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada;
9Canadian Institute for Advanced Research (CIFAR), Toronto, ON
Ryan K.C. Yuen
1Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
Karun K. Singh
3Stem Cell and Cancer Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada;
James Ellis
4Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
8Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada;
Stephen W. Scherer
1Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada;
2The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada;
8Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada;
9Canadian Institute for Advanced Research (CIFAR), Toronto, ON
10McLaughlin Centre, University of Toronto, Toronto, ON, Canada
Article usage
Posted July 14, 2018.
CNTN5−/+ or EHMT2−/+ iPSC-Derived Neurons from Individuals with Autism Develop Hyperactive Neuronal Networks
Eric Deneault, Muhammad Faheem, Sean H. White, Deivid C. Rodrigues, Song Sun, Wei Wei, Alina Piekna, Tadeo Thompson, Jennifer L. Howe, Leon Chalil, Vickie Kwan, Susan Walker, Peter Pasceri, Frederick P. Roth, Ryan K.C. Yuen, Karun K. Singh, James Ellis, Stephen W. Scherer
bioRxiv 368928; doi: https://doi.org/10.1101/368928
CNTN5−/+ or EHMT2−/+ iPSC-Derived Neurons from Individuals with Autism Develop Hyperactive Neuronal Networks
Eric Deneault, Muhammad Faheem, Sean H. White, Deivid C. Rodrigues, Song Sun, Wei Wei, Alina Piekna, Tadeo Thompson, Jennifer L. Howe, Leon Chalil, Vickie Kwan, Susan Walker, Peter Pasceri, Frederick P. Roth, Ryan K.C. Yuen, Karun K. Singh, James Ellis, Stephen W. Scherer
bioRxiv 368928; doi: https://doi.org/10.1101/368928
Subject Area
Subject Areas
- Biochemistry (11736)
- Bioengineering (8746)
- Bioinformatics (29186)
- Biophysics (14964)
- Cancer Biology (12084)
- Cell Biology (17401)
- Clinical Trials (138)
- Developmental Biology (9418)
- Ecology (14176)
- Epidemiology (2067)
- Evolutionary Biology (18299)
- Genetics (12235)
- Genomics (16793)
- Immunology (11863)
- Microbiology (28066)
- Molecular Biology (11580)
- Neuroscience (60925)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4956)
- Plant Biology (10422)
- Synthetic Biology (2883)
- Systems Biology (7338)
- Zoology (1650)