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Cortical Column and Whole Brain Imaging of Neural Circuits with Molecular Contrast and Nanoscale Resolution
View ORCID ProfileRuixuan Gao, Shoh M. Asano, View ORCID ProfileSrigokul Upadhyayula, Pisarev Igor, View ORCID ProfileDaniel E. Milkie, View ORCID ProfileTsung-Li Liu, Singh Ved, View ORCID ProfileGraves Austin, Grace H. Huynh, View ORCID ProfileYongxin Zhao, View ORCID ProfileJohn Bogovic, Jennifer Colonell, View ORCID ProfileCarolyn M. Ott, Christopher Zugates, Susan Tappan, Alfredo Rodriguez, View ORCID ProfileKishore R. Mosaliganti, View ORCID ProfileSean G. Megason, View ORCID ProfileJennifer Lippincott-Schwartz, View ORCID ProfileAdam Hantman, View ORCID ProfileGerald M. Rubin, View ORCID ProfileTom Kirchhausen, View ORCID ProfileStephan Saalfeld, View ORCID ProfileYoshinori Aso, Edward S. Boyden, View ORCID ProfileEric Betzig
doi: https://doi.org/10.1101/374140
Ruixuan Gao
1MIT Media Lab, MIT, Cambridge, MA 02139, USA.
2McGovern Institute for Brain Research, MIT, Cambridge, MA 02139, USA.
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Shoh M. Asano
1MIT Media Lab, MIT, Cambridge, MA 02139, USA.
2McGovern Institute for Brain Research, MIT, Cambridge, MA 02139, USA.
Srigokul Upadhyayula
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
4Department of Cell Biology, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
5Program in Cellular and Molecular Medicine, Boston Children’s Hospital, 200 Longwood Ave, Boston, MA 02115, USA.
6Department of Pediatrics, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
Pisarev Igor
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Daniel E. Milkie
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Tsung-Li Liu
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Singh Ved
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Graves Austin
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Grace H. Huynh
1MIT Media Lab, MIT, Cambridge, MA 02139, USA.
Yongxin Zhao
1MIT Media Lab, MIT, Cambridge, MA 02139, USA.
John Bogovic
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Jennifer Colonell
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Carolyn M. Ott
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Christopher Zugates
7arivis AG, United States, 1875 Connecticut Ave NW, 10th floor, Washington, DC 20009, USA.
Susan Tappan
8MBF Bioscience, 185 Allen Brook Ln, Suite 101, Williston, VT 05495, USA.
Alfredo Rodriguez
8MBF Bioscience, 185 Allen Brook Ln, Suite 101, Williston, VT 05495, USA.
Kishore R. Mosaliganti
9Department of Systems Biology, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
Sean G. Megason
9Department of Systems Biology, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
Jennifer Lippincott-Schwartz
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Adam Hantman
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Gerald M. Rubin
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Tom Kirchhausen
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
4Department of Cell Biology, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
5Program in Cellular and Molecular Medicine, Boston Children’s Hospital, 200 Longwood Ave, Boston, MA 02115, USA.
6Department of Pediatrics, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA.
Stephan Saalfeld
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Yoshinori Aso
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Edward S. Boyden
1MIT Media Lab, MIT, Cambridge, MA 02139, USA.
2McGovern Institute for Brain Research, MIT, Cambridge, MA 02139, USA.
10Department of Biological Engineering, MIT, Cambridge, MA 02139, USA.
11MIT Center for Neurobiological Engineering, MIT, Cambridge, MA 02139, USA.
12Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA.
13Koch Institute, MIT, Cambridge, MA 02139, USA.
Eric Betzig
3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
14Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
15Department of Physics, University of California, Berkeley, CA 94720, USA
16Howard Hughes Medical Institute, Berkeley, CA 94720, USA
17Helen Wills Neuroscience Institute, Berkeley, CA 94720, USA
18Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
Article usage
Posted July 23, 2018.
Cortical Column and Whole Brain Imaging of Neural Circuits with Molecular Contrast and Nanoscale Resolution
Ruixuan Gao, Shoh M. Asano, Srigokul Upadhyayula, Pisarev Igor, Daniel E. Milkie, Tsung-Li Liu, Singh Ved, Graves Austin, Grace H. Huynh, Yongxin Zhao, John Bogovic, Jennifer Colonell, Carolyn M. Ott, Christopher Zugates, Susan Tappan, Alfredo Rodriguez, Kishore R. Mosaliganti, Sean G. Megason, Jennifer Lippincott-Schwartz, Adam Hantman, Gerald M. Rubin, Tom Kirchhausen, Stephan Saalfeld, Yoshinori Aso, Edward S. Boyden, Eric Betzig
bioRxiv 374140; doi: https://doi.org/10.1101/374140
Cortical Column and Whole Brain Imaging of Neural Circuits with Molecular Contrast and Nanoscale Resolution
Ruixuan Gao, Shoh M. Asano, Srigokul Upadhyayula, Pisarev Igor, Daniel E. Milkie, Tsung-Li Liu, Singh Ved, Graves Austin, Grace H. Huynh, Yongxin Zhao, John Bogovic, Jennifer Colonell, Carolyn M. Ott, Christopher Zugates, Susan Tappan, Alfredo Rodriguez, Kishore R. Mosaliganti, Sean G. Megason, Jennifer Lippincott-Schwartz, Adam Hantman, Gerald M. Rubin, Tom Kirchhausen, Stephan Saalfeld, Yoshinori Aso, Edward S. Boyden, Eric Betzig
bioRxiv 374140; doi: https://doi.org/10.1101/374140
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