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- March 4, 2019.
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- Version 1 (August 9, 2018 - 15:57).
- Version 2 (February 11, 2019 - 20:03).
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license.
Author Information
- Mike A. Nalls1,2,CA*,
- Cornelis Blauwendraat1*,
- Costanza L. Vallerga3,4*,
- Karl Heilbron5*,
- Sara Bandres-Ciga1*,
- Diana Chang6*,
- Manuela Tan7,
- Demis A. Kia7,
- Alastair J. Noyce7,8,
- Angli Xue3,4,
- Jose Bras9,10,
- Emily Young11,
- Rainer von Coelln12,
- Javier Simón-Sánchez13,14,
- Claudia Schulte13,14,
- Manu Sharma15,
- Lynne Krohn16,17,
- Lasse Pihlstrom18,
- Ari Siitonen19,20,
- Hirotaka Iwaki12,21,
- Hampton Leonard12,
- Faraz Faghri122,
- J. Raphael Gibbs1,
- Dena G. Hernandez1,
- Sonja W. Scholz23,24,
- Juan A. Botia7,25,
- Maria Martinez26,
- Jean-Christophe Corvol27,
- Suzanne Lesage27,
- Joseph Jankovic11,
- Lisa M. Shulman11,
- The 23andMe Research Team5,
- System Genomics of Parkinson’s Disease (SGPD) Consortium,
- Margaret Sutherland28,
- Pentti Tienari29,30,
- Kari Majamaa19,20,
- Mathias Toft18,31,
- Ole A. Andreassen32,33,
- Tushar Bangale6,
- Alexis Brice27,
- Jian Yang3,4,
- Ziv Gan-Or16,17,34,
- Thomas Gasser13,14,
- Peter Heutink13,14,
- Joshua M Shulman11,35,36,
- Nicolas Wood7,
- David A. Hinds5,
- John A. Hardy7,
- Huw R Morris37,38,
- Jacob Gratten3,4,
- Peter M. Visscher3,4,
- Robert R. Graham6,
- Andrew B. Singleton1,
- for the International Parkinson’s Disease Genomics Consortium
- 1Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892 USA
- 2Data Tecnica International, Glen Echo, MD, 20812 USA
- 3Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072 Australia
- 4Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072 Australia
- 523andMe, Inc., Mountain View, California 94041 USA
- 6Department of Human Genetics, Genentech, South San Francisco, 94080, CA, USA
- 7Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
- 8Preventive Neurology Unit, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
- 9Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, USA
- 10Department of Neurodegenerative Diseases, UCL Institute of Neurology, University College London, London, UK
- 11Department of Neurology, Baylor College of Medicine, Houston, USA
- 12Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
- 13Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
- 14German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
- 15Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tubingen, Germany
- 16Department of Human Genetics, McGill University, Montreal, Quebec, Canada
- 17Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
- 18Department of Neurology, Oslo University Hospital, Oslo, Norway
- 19Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland
- 20Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland
- 21The Michael J. Fox Foundation, New York, New York, 10036 USA
- 22Department of Computer Science, University of Illinois Urbana-Champaign, Champaign, IL, 61820, USA
- 23Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
- 24Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD 21287, USA
- 25Departamento de Ingeniería de la Información y las Comunicaciones, Universidad de Murcia, Spain
- 26INSERM UMR 1220; and Paul Sabatier University, Toulouse, France
- 27INSERM U1127, CNRS UMR 7225, Sorbonne Université UMR S1127, APHP, Institut du Cerveau et de la Moelle épinière, ICM, Paris F-75013, France
- 28National Institute on Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892 USA
- 29Clinical Neurosciences, Neurology, University of Helsinki, Helsinki, Finland
- 30Helsinki University Hospital, Helsinki, Finland
- 31Institute of Clinical Medicine, University of Oslo, Oslo, Norway
- 32Jebsen Centre for Psychosis Research, University of Oslo, Oslo, Norway
- 33Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
- 34Department of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada
- 35Departments of Molecular & Human Genetics and Neuroscience, Baylor College of Medicine, Houston, USA
- 36Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston
- 37Department of Clinical Neuroscience, UCL Institute of Neurology, London UK
- 38UCL Movement Disorders Centre, UCL Institute of Neurology, London, UK
- ↵CAdenotes corresponding author, mike{at}datatecnica.com
↵* denotes shared first authorship.