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Systems therapeutics analyses identify genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer

View ORCID ProfileIman Tavassoly, Yuan Hu, Shan Zhao, Chiara Mariottini, Aislyn Boran, Yibang Chen, Lisa Li, Rosa E. Tolentino, Gomathi Jayaraman, Joseph Goldfarb, James Gallo, View ORCID ProfileRavi Iyengar
doi: https://doi.org/10.1101/396697
Iman Tavassoly
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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  • ORCID record for Iman Tavassoly
Yuan Hu
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
2Clinical Pharmacology and Pharmacy, Chinese PLA General Hospital, Beijing, PRC
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Shan Zhao
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Chiara Mariottini
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Aislyn Boran
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Yibang Chen
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Lisa Li
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Rosa E. Tolentino
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Gomathi Jayaraman
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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Joseph Goldfarb
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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James Gallo
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
3Present address: Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Albany NY
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Ravi Iyengar
1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
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  • ORCID record for Ravi Iyengar
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Article Information

doi 
https://doi.org/10.1101/396697
History 
  • August 21, 2018.

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  • You are currently viewing Version 1 of this article (August 21, 2018 - 12:19).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Iman Tavassoly1,*,
  2. Yuan Hu1,2,*,
  3. Shan Zhao1,*,
  4. Chiara Mariottini1,
  5. Aislyn Boran1,
  6. Yibang Chen1,
  7. Lisa Li1,
  8. Rosa E. Tolentino1,
  9. Gomathi Jayaraman1,
  10. Joseph Goldfarb1,
  11. James Gallo1,3 and
  12. Ravi Iyengar1
  1. 1Department of Pharmacological Sciences and Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York NY 10029
  2. 2Clinical Pharmacology and Pharmacy, Chinese PLA General Hospital, Beijing, PRC
  3. 3Present address: Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Albany NY
  1. Address correspondence to: Ravi Iyengar, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave., Rm 12-70, New York NY 10029, e-mail: ravi.iyengar{at}mssm.edu, Phone: 212-659-1707
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Posted August 21, 2018.
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Systems therapeutics analyses identify genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer
Iman Tavassoly, Yuan Hu, Shan Zhao, Chiara Mariottini, Aislyn Boran, Yibang Chen, Lisa Li, Rosa E. Tolentino, Gomathi Jayaraman, Joseph Goldfarb, James Gallo, Ravi Iyengar
bioRxiv 396697; doi: https://doi.org/10.1101/396697
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Systems therapeutics analyses identify genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer
Iman Tavassoly, Yuan Hu, Shan Zhao, Chiara Mariottini, Aislyn Boran, Yibang Chen, Lisa Li, Rosa E. Tolentino, Gomathi Jayaraman, Joseph Goldfarb, James Gallo, Ravi Iyengar
bioRxiv 396697; doi: https://doi.org/10.1101/396697

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