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Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis
Vahid Kheirollahi, Roxana M. Wasnick, Valentina Biasin, Ana Ivonne Vazquez-Armendariz, Xuran Chu, Alena Moiseenko, Astrid Weiss, Jochen Wilhelm, Jin-San Zhang, Grazyna Kwapiszewska, Susanne Herold, Ralph T. Schermuly, Werner Seeger, Andreas Günther, Saverio Bellusci, View ORCID ProfileElie El Agha
doi: https://doi.org/10.1101/401265
Vahid Kheirollahi
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Roxana M. Wasnick
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Valentina Biasin
2Ludwig Boltzmann Institute for Lung Vascular Research, Otto Loewi Research Center, Medical University Graz, Graz, Austria
Ana Ivonne Vazquez-Armendariz
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Xuran Chu
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
3College of Life and Environmental Sciences, Wenzhou Medical University, Wenzhou, China
Alena Moiseenko
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Astrid Weiss
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Jochen Wilhelm
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Jin-San Zhang
3College of Life and Environmental Sciences, Wenzhou Medical University, Wenzhou, China
Grazyna Kwapiszewska
2Ludwig Boltzmann Institute for Lung Vascular Research, Otto Loewi Research Center, Medical University Graz, Graz, Austria
Susanne Herold
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Ralph T. Schermuly
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Werner Seeger
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Andreas Günther
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
Saverio Bellusci
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
3College of Life and Environmental Sciences, Wenzhou Medical University, Wenzhou, China
Elie El Agha
1Excellence Cluster Cardio-Pulmonary System (ECCPS) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Giessen, Germany
3College of Life and Environmental Sciences, Wenzhou Medical University, Wenzhou, China
Posted September 26, 2018.
Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis
Vahid Kheirollahi, Roxana M. Wasnick, Valentina Biasin, Ana Ivonne Vazquez-Armendariz, Xuran Chu, Alena Moiseenko, Astrid Weiss, Jochen Wilhelm, Jin-San Zhang, Grazyna Kwapiszewska, Susanne Herold, Ralph T. Schermuly, Werner Seeger, Andreas Günther, Saverio Bellusci, Elie El Agha
bioRxiv 401265; doi: https://doi.org/10.1101/401265
Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis
Vahid Kheirollahi, Roxana M. Wasnick, Valentina Biasin, Ana Ivonne Vazquez-Armendariz, Xuran Chu, Alena Moiseenko, Astrid Weiss, Jochen Wilhelm, Jin-San Zhang, Grazyna Kwapiszewska, Susanne Herold, Ralph T. Schermuly, Werner Seeger, Andreas Günther, Saverio Bellusci, Elie El Agha
bioRxiv 401265; doi: https://doi.org/10.1101/401265
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