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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy
doi: https://doi.org/10.1101/401521
Young-Ho Lee
aInstitute for Protein research, Osaka University Yamadaoka 3-2, Suita, Osaka 565-0871, Japan.
bProtein Structure Research Group, Division of Bioconvergence Analysis, Korea Basic Science Institute, Chungcheongbuk-do 28119, South Korea.
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Yuxi Lin
cDepartment of Chemistry, Sookmyung Women’s University Cheongpa-ro 47-gil 100, Yongsangu, Seoul 04310, South Korea.
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Sarah J. Cox
dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:
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  • For correspondence: ramamoor@umich.edu
Misaki Kinoshita
aInstitute for Protein research, Osaka University Yamadaoka 3-2, Suita, Osaka 565-0871, Japan.
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Bikash R. Sahoo
dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:
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  • For correspondence: ramamoor@umich.edu
Magdalena Ivanova
eDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA
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Ayyalusamy Ramamoorthy
dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:
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  • For correspondence: ramamoor@umich.edu
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Article Information

doi 
https://doi.org/10.1101/401521
History 
  • August 27, 2018.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Young-Ho Leea,b,†,
  2. Yuxi Linc,†,
  3. Sarah J. Coxd,
  4. Misaki Kinoshitaa,
  5. Bikash R. Sahood,
  6. Magdalena Ivanovae and
  7. Ayyalusamy Ramamoorthyd
  1. aInstitute for Protein research, Osaka University Yamadaoka 3-2, Suita, Osaka 565-0871, Japan.
  2. bProtein Structure Research Group, Division of Bioconvergence Analysis, Korea Basic Science Institute, Chungcheongbuk-do 28119, South Korea.
  3. cDepartment of Chemistry, Sookmyung Women’s University Cheongpa-ro 47-gil 100, Yongsangu, Seoul 04310, South Korea.
  4. dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail: ramamoor{at}umich.edu
  5. eDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA
  1. ↵† These authors contributed equally to this work.

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Posted August 27, 2018.
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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane
Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy
bioRxiv 401521; doi: https://doi.org/10.1101/401521
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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane
Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy
bioRxiv 401521; doi: https://doi.org/10.1101/401521

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