Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Young-Ho Lee; Yuxi Lin; Sarah J. Cox; Misaki Kinoshita; Bikash R. Sahoo; Magdalena Ivanova; Ayyalusamy Ramamoorthy

doi:10.1101/401521

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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy

doi: https://doi.org/10.1101/401521

Young-Ho Lee

aInstitute for Protein research, Osaka University Yamadaoka 3-2, Suita, Osaka 565-0871, Japan.

bProtein Structure Research Group, Division of Bioconvergence Analysis, Korea Basic Science Institute, Chungcheongbuk-do 28119, South Korea.

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Yuxi Lin

cDepartment of Chemistry, Sookmyung Women’s University Cheongpa-ro 47-gil 100, Yongsangu, Seoul 04310, South Korea.

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Sarah J. Cox

dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:

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For correspondence: ramamoor@umich.edu

Misaki Kinoshita

aInstitute for Protein research, Osaka University Yamadaoka 3-2, Suita, Osaka 565-0871, Japan.

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Bikash R. Sahoo

dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:

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For correspondence: ramamoor@umich.edu

Magdalena Ivanova

eDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA

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Ayyalusamy Ramamoorthy

dBiophysics and Department of Chemistry, University of Michigan Ann Arbor, MI 48109-1055, USA. E-mail:

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For correspondence: ramamoor@umich.edu

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Posted August 27, 2018.

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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy

bioRxiv 401521; doi: https://doi.org/10.1101/401521

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Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova, Ayyalusamy Ramamoorthy

bioRxiv 401521; doi: https://doi.org/10.1101/401521

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