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MMseqs2 desktop and local web server app for fast, interactive sequence searches

Milot Mirdita, Martin Steinegger, Johannes Söding
doi: https://doi.org/10.1101/419895
Milot Mirdita
1Quantitative and Computational Biology group, Max-Planck Institute for Biophysical Chemistry Am Faßberg 11 37077 Göttingen, Germany
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Martin Steinegger
1Quantitative and Computational Biology group, Max-Planck Institute for Biophysical Chemistry Am Faßberg 11 37077 Göttingen, Germany
2Department of Chemistry, Seoul National University, Seoul, Korea
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Johannes Söding
1Quantitative and Computational Biology group, Max-Planck Institute for Biophysical Chemistry Am Faßberg 11 37077 Göttingen, Germany
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Summary

The MMseqs2 desktop and web server app facilitates interactive sequence searches through custom protein sequence and profile databases on personal workstations. By eliminating MMseqs2’s runtime overhead, we reduced response times to a few seconds at sensitivities close to BLAST.

Availability and implementation The app is easy to install for non-experts. Source code, prebuilt desktop app packages for Windows, macOS and Linux, Docker images for the web server application, and a demo web server are available at https://search.mmseqs.com.

Contact martin.steinegger{at}mpibpc.mpg.de or soeding{at}mpibpc.mpg.de

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted September 18, 2018.
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MMseqs2 desktop and local web server app for fast, interactive sequence searches
Milot Mirdita, Martin Steinegger, Johannes Söding
bioRxiv 419895; doi: https://doi.org/10.1101/419895
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MMseqs2 desktop and local web server app for fast, interactive sequence searches
Milot Mirdita, Martin Steinegger, Johannes Söding
bioRxiv 419895; doi: https://doi.org/10.1101/419895

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