New Results
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 90,000 patients across three healthcare systems
Amanda B Zheutlin, Jessica Dennis, Nicole Restrepo, Peter Straub, Douglas Ruderfer, Victor M Castro, Chia-Yen Chen, H. Lester Kirchner, Christopher F. Chabris, Lea K Davis, Jordan W Smoller
doi: https://doi.org/10.1101/421164
Amanda B Zheutlin
1Psychiatric & Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA
Jessica Dennis
2Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
3Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN
Nicole Restrepo
4Department of Biomedical & Translational Informatics, Geisinger, Rockville, MD
Peter Straub
2Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
3Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN
Douglas Ruderfer
2Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
3Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN
5Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN
Victor M Castro
6Research Information Science and Computing, Partners HealthCare, Somerville, MA
Chia-Yen Chen
1Psychiatric & Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA
7Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA
8Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA
H. Lester Kirchner
4Department of Biomedical & Translational Informatics, Geisinger, Rockville, MD
Christopher F. Chabris
9Autism and Developmental Medicine Institute, Geisinger, Lewisburg, PA
Lea K Davis
2Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
3Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN
Jordan W Smoller
1Psychiatric & Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA
7Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA
Posted September 18, 2018.
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 90,000 patients across three healthcare systems
Amanda B Zheutlin, Jessica Dennis, Nicole Restrepo, Peter Straub, Douglas Ruderfer, Victor M Castro, Chia-Yen Chen, H. Lester Kirchner, Christopher F. Chabris, Lea K Davis, Jordan W Smoller
bioRxiv 421164; doi: https://doi.org/10.1101/421164
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 90,000 patients across three healthcare systems
Amanda B Zheutlin, Jessica Dennis, Nicole Restrepo, Peter Straub, Douglas Ruderfer, Victor M Castro, Chia-Yen Chen, H. Lester Kirchner, Christopher F. Chabris, Lea K Davis, Jordan W Smoller
bioRxiv 421164; doi: https://doi.org/10.1101/421164
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