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History
- September 23, 2018.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Xueping Liu1,a,
- Dorte Helenius2,3,a,
- Line Skotte1,a,
- Robin N. Beaumont4,
- Matthias Wielscher5,
- Frank Geller1,
- Julius Juodakis6,
- Anubha Mahajan7,
- Jonathan P. Bradfield8,9,
- Frederick T.J. Lin10,
- Suzanne Vogelezang11,12,13,
- Mariona Bustamante14,15,16,
- Tarunveer S. Ahluwalia17,
- Niina Pitkänen18,
- Carol A. Wang19,
- Jonas Bacelis20,
- Maria C. Borges21,22,
- Ge Zhang23,24,25,
- Bruce A. Bedell26,
- Robert M. Rossi25,27,
- Kristin Skogstrand2,28,
- Shouneng Peng29,30,
- Early Growth Genetics (EGG) Consortiumb,
- iPSYCH-BROAD Working Groupc,
- Wesley K. Thompson2,3,
- Vivek Appadurai2,3,
- Debbie A. Lawlor21,22,31,
- Ilkka Kalliala32,33,
- Christine Power34,
- Mark I. McCarthy7,35,36,
- Heather A. Boyd1,
- Mary L. Marazita37,38,
- Hakon Hakonarson8,39,40,
- M. Geoffrey Hayes10,41,42,
- Denise M. Scholtens43,
- Fernando Rivadeneira11,12,44,
- Vincent W.V. Jaddoe11,12,13,
- Rebecca K. Vinding17,
- Hans Bisgaard17,
- Bridget A. Knight45,
- Katja Pahkala18,46,
- Olli Raitakari18,47,
- Øyvind Helgeland48,49,50,
- Stefan Johansson48,51,
- Pål R. Njølstad48,49,
- João Fadista1,
- Andrew Schork2,3,
- Ron Nudel2,3,
- Daniel E. Miller52,
- Xiaoting Chen52,
- Matthew T. Weirauch27,52,53,
- Preben Bo Mortensen2,54,55,
- Anders D. Børglum2,55,56,
- Merete Nordentoft2,57,58,
- Ole Mors2,59,
- Ke Hao29,30,
- Kelli K. Ryckman26,60,
- David M. Hougaard2,28,
- Leah C. Kottyan27,52,
- Craig E. Pennell19,
- Leo-Pekka Lyytikainen61,62,
- Klaus Bønnelykke17,
- Martine Vrijheid14,15,16,
- Janine F. Felix11,12,13,
- William L. Lowe Jr.10,
- Struan F.A. Grant8,39,40,
- Elina Hyppönen34,63,64,
- Bo Jacobsson6,65,
- Marjo-Riitta Jarvelin66,67,
- Louis J. Muglia23,24,25,27,
- Jeffrey C. Murray26,
- Rachel M. Freathy4,68,
- Thomas M. Werge2,3,58,
- Mads Melbye1,69,
- Alfonso Buil2,3,d and
- Bjarke Feenstra1,d
- 1Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
- 2iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
- 3Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Copenhagen, Roskilde, Denmark.
- 4Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
- 5Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
- 6Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
- 7Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
- 8Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
- 9Quantinuum Research, LLC, San Diego, CA, USA.
- 10Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
- 11The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
- 12Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
- 13Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
- 14ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
- 15Universitat Pompeu Fabra (UPF), Barcelona, Spain.
- 16CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
- 17COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
- 18Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.
- 19School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, New South Wales, Australia.
- 20Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden.
- 21MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
- 22Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
- 23Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
- 24Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
- 25March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati, OH, USA.
- 26Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
- 27Department of Pediatrics, University of Cincinnati College of Medicine. Cincinnati, OH, USA.
- 28Statens Serum Institut, Center for Neonatal Screening, Department for Congenital Disorders, Copenhagen, Denmark.
- 29Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA.
- 30Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA.
- 31NIHR Bristol Biomedical Research Centre, Bristol, UK.
- 32Department of Surgery and Cancer, IRDB, Faculty of Medicine, Imperial College, London W12 0NN, UK.
- 33Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 2, 00029 HUS, Finland.
- 34Population, Policy and Practice, Great Ormond Street Institute for Child Health, University College London, London, UK.
- 35Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
- 36NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LJ, UK.
- 37Center for Craniofacial and Dental Genetics, Department of Oral Biology School of Dental Medicine University of Pittsburgh, Pittsburgh, PA, USA.
- 38Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
- 39Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
- 40Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
- 41Department of Anthropology, Northwestern University, Evanston, IL, USA.
- 42Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
- 43Division of Biostatistics, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
- 44Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
- 45NIHR Exeter Clinical Research Facility, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
- 46Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Health and Physical Activity, University of Turku, 20520 Turku, Finland.
- 47Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, 20521 Turku, Finland.
- 48K. G. Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
- 49Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
- 50Norwegian Institute of Public Health, Division of Health data and Digitalization, Department of Genetic Research and Bioinformatics, Oslo, Norway.
- 51Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
- 52Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
- 53Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children’s Hospital, Cincinnati, Ohio, USA.
- 54National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
- 55iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
- 56Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark.
- 57Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
- 58Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 59Psychosis Research Unit, Aarhus University Hospital, Risskov, Denmark.
- 60Department of Epidemiology, University of Iowa, Iowa City, IA, USA.
- 61Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.
- 62Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland.
- 63Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, Australia.
- 64South Australian Health and Medical Research Institute, Adelaide, Australia.
- 65Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
- 66Institute of Health Sciences, University of Oulu, Oulu, Finland.
- 67Department of Epidemiology and Biostatistics, School of Public Health, Medical Research Council-Health Protection Agency Centre for Environment and Health, Faculty of Medicine, Imperial College London, UK.
- 68Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove Bristol, BS8 2BN, UK.
- 69Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
- Correspondence should be addressed to B.F. (fee{at}ssi.dk).
↵a These authors contributed equally to this work.