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Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites
Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee, Hyunyoung Jeong
doi: https://doi.org/10.1101/426197
Yukuang Guo
1Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago
5Center for Biomolecular Sciences
Camila Manoel Crnkovic
1Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago
Kyoung-Jae Won
2Department of Pharmacy Practice, University of Illinois at Chicago
Xiaotong Yang
4Department of Biopharmaceutical Sciences, University of Illinois at Chicago
John Richard Lee
3Division of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine
Jimmy Orjala
1Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago
5Center for Biomolecular Sciences
Hyunwoo Lee
1Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago
5Center for Biomolecular Sciences
Hyunyoung Jeong
2Department of Pharmacy Practice, University of Illinois at Chicago
4Department of Biopharmaceutical Sciences, University of Illinois at Chicago
5Center for Biomolecular Sciences
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Posted October 01, 2018.
Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites
Yukuang Guo, Camila Manoel Crnkovic, Kyoung-Jae Won, Xiaotong Yang, John Richard Lee, Jimmy Orjala, Hyunwoo Lee, Hyunyoung Jeong
bioRxiv 426197; doi: https://doi.org/10.1101/426197
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