Regional heterogeneity in gene expression, regulation and coherence in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia

L Collado-Torres; EE Burke; A Peterson; JH Shin; RE Straub; A Rajpurohit; SA Semick; WS Ulrich; Consortium BrainSeq; C Valencia; R Tao; A Deep-Soboslay; TM Hyde; JE Kleinman; DR Weinberger; AE Jaffe

doi:10.1101/426213

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Regional heterogeneity in gene expression, regulation and coherence in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia

View ORCID ProfileL Collado-Torres, EE Burke, A Peterson, JH Shin, RE Straub, A Rajpurohit, View ORCID ProfileSA Semick, WS Ulrich, Consortium BrainSeq, C Valencia, R Tao, A Deep-Soboslay, TM Hyde, JE Kleinman, DR Weinberger, View ORCID ProfileAE Jaffe

doi: https://doi.org/10.1101/426213

L Collado-Torres

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Center for Computational Biology, Johns Hopkins University, Baltimore, MD, USA

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ORCID record for L Collado-Torres

EE Burke

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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A Peterson

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

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JH Shin

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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RE Straub

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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A Rajpurohit

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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SA Semick

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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ORCID record for SA Semick

WS Ulrich

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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Consortium BrainSeq

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C Valencia

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

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R Tao

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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A Deep-Soboslay

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA

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TM Hyde

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JE Kleinman

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA

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DR Weinberger

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA

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For correspondence: drweinberger@libd.org andrew.jaffe@libd.org

AE Jaffe

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA Center for Computational Biology, Johns Hopkins University, Baltimore, MD, USA Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

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For correspondence: drweinberger@libd.org andrew.jaffe@libd.org

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Regional heterogeneity in gene expression, regulation and coherence in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia

L Collado-Torres, EE Burke, A Peterson, JH Shin, RE Straub, A Rajpurohit, SA Semick, WS Ulrich, Consortium BrainSeq, C Valencia, R Tao, A Deep-Soboslay, TM Hyde, JE Kleinman, DR Weinberger, AE Jaffe

bioRxiv 426213; doi: https://doi.org/10.1101/426213

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Regional heterogeneity in gene expression, regulation and coherence in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia

L Collado-Torres, EE Burke, A Peterson, JH Shin, RE Straub, A Rajpurohit, SA Semick, WS Ulrich, Consortium BrainSeq, C Valencia, R Tao, A Deep-Soboslay, TM Hyde, JE Kleinman, DR Weinberger, AE Jaffe

bioRxiv 426213; doi: https://doi.org/10.1101/426213

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