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Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila
Sebastian M. Bernasek, Suzy SJ Hur, Nicolás Peláez-Restrepo, Jean-François Boisclair Lachance, Rachael Bakker, Heliodoro Tejedor Navarro, Nicelio Sanchez-Luege, View ORCID ProfileLuís A. N. Amaral, Neda Bagheri, Ilaria Rebay, View ORCID ProfileRichard W. Carthew
doi: https://doi.org/10.1101/430744
Sebastian M. Bernasek
1Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL
Suzy SJ Hur
2Ben May Department for Cancer Research, University of Chicago, Chicago, IL
Nicolás Peláez-Restrepo
1Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL
3Department of Molecular Biosciences, Northwestern University, Evanston, IL
4Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA
10Howard Hughes Medical Institute (HHMI), Hanna H. Gray Fellows Program
Jean-François Boisclair Lachance
2Ben May Department for Cancer Research, University of Chicago, Chicago, IL
Rachael Bakker
3Department of Molecular Biosciences, Northwestern University, Evanston, IL
Heliodoro Tejedor Navarro
6Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL
Nicelio Sanchez-Luege
2Ben May Department for Cancer Research, University of Chicago, Chicago, IL
Luís A. N. Amaral
1Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL
5Department of Physics and Astronomy, Northwestern University, Evanston, IL
6Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL
7NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL
Neda Bagheri
1Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL
6Northwestern Institute on Complex Systems, Northwestern University, Evanston, IL
7NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL
8Chemistry of Life Processes, Northwestern University, Evanston, IL
Ilaria Rebay
2Ben May Department for Cancer Research, University of Chicago, Chicago, IL
Richard W. Carthew
3Department of Molecular Biosciences, Northwestern University, Evanston, IL
7NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, IL
9Department of Biochemistry and Molecular Genetics, Northwestern University, Evanston, IL
Posted November 21, 2022.
Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila
Sebastian M. Bernasek, Suzy SJ Hur, Nicolás Peláez-Restrepo, Jean-François Boisclair Lachance, Rachael Bakker, Heliodoro Tejedor Navarro, Nicelio Sanchez-Luege, Luís A. N. Amaral, Neda Bagheri, Ilaria Rebay, Richard W. Carthew
bioRxiv 430744; doi: https://doi.org/10.1101/430744
Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila
Sebastian M. Bernasek, Suzy SJ Hur, Nicolás Peláez-Restrepo, Jean-François Boisclair Lachance, Rachael Bakker, Heliodoro Tejedor Navarro, Nicelio Sanchez-Luege, Luís A. N. Amaral, Neda Bagheri, Ilaria Rebay, Richard W. Carthew
bioRxiv 430744; doi: https://doi.org/10.1101/430744
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