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Human neurons from Christianson syndrome iPSCs reveal allele-specific responses to rescue strategies
View ORCID ProfileSofia B. Lizarraga, Abbie M. Maguire, Li Ma, Laura I. van Dyck, Qing Wu, Dipal Nagda, Liane L. Livi, Matthew F. Pescosolido, Michael Schmidt, Shanique Alabi, Mara H. Cowen, Paul Brito-Vargas, Diane Hoffman-Kim, Ece D. Gamsiz Uzun, Avner Schlessinger, Richard N. Jones, View ORCID ProfileEric M. Morrow
doi: https://doi.org/10.1101/444232
Sofia B. Lizarraga
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA
2Center for Childhood Neurotherapeutics, University of South Carolina, Columbia, South Carolina, USA
Abbie M. Maguire
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
4Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island, USA
Li Ma
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
Laura I. van Dyck
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
Qing Wu
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
Dipal Nagda
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
Liane L. Livi
5Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, USA
Matthew F. Pescosolido
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
4Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island, USA
Michael Schmidt
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
4Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island, USA
Shanique Alabi
6Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Mara H. Cowen
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA
2Center for Childhood Neurotherapeutics, University of South Carolina, Columbia, South Carolina, USA
Paul Brito-Vargas
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA
2Center for Childhood Neurotherapeutics, University of South Carolina, Columbia, South Carolina, USA
Diane Hoffman-Kim
5Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, USA
7Carney Institute for Brain Science, Brown University, Providence, Rhode Island, USA
8Center for Biomedical Engineering, Brown University, Providence, Rhode Island, USA
Ece D. Gamsiz Uzun
9Department of Pathology and Laboratory Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
10Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, USA
Avner Schlessinger
6Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Richard N. Jones
11Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
Eric M. Morrow
3Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA
4Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island, USA
7Carney Institute for Brain Science, Brown University, Providence, Rhode Island, USA
10Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, USA
11Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
12Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, East Providence, Rhode Island, USA
Article usage
Posted October 16, 2018.
Human neurons from Christianson syndrome iPSCs reveal allele-specific responses to rescue strategies
Sofia B. Lizarraga, Abbie M. Maguire, Li Ma, Laura I. van Dyck, Qing Wu, Dipal Nagda, Liane L. Livi, Matthew F. Pescosolido, Michael Schmidt, Shanique Alabi, Mara H. Cowen, Paul Brito-Vargas, Diane Hoffman-Kim, Ece D. Gamsiz Uzun, Avner Schlessinger, Richard N. Jones, Eric M. Morrow
bioRxiv 444232; doi: https://doi.org/10.1101/444232
Human neurons from Christianson syndrome iPSCs reveal allele-specific responses to rescue strategies
Sofia B. Lizarraga, Abbie M. Maguire, Li Ma, Laura I. van Dyck, Qing Wu, Dipal Nagda, Liane L. Livi, Matthew F. Pescosolido, Michael Schmidt, Shanique Alabi, Mara H. Cowen, Paul Brito-Vargas, Diane Hoffman-Kim, Ece D. Gamsiz Uzun, Avner Schlessinger, Richard N. Jones, Eric M. Morrow
bioRxiv 444232; doi: https://doi.org/10.1101/444232
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