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Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
Salah Mahmoudi, Elena Mancini, Alessandra Moore, Lucy Xu, Fereshteh Jahanbani, Katja Hebestreit, Rajini Srinivasan, Xiyan Li, Keerthana Devarajan, Laurie Prélot, Cheen Euong Ang, Yohei Shibuya, Bérénice A. Benayoun, Anne Lynn S. Chang, Marius Wernig, Joanna Wysocka, Michael T. Longaker, Michael P. Snyder, Anne Brunet
doi: https://doi.org/10.1101/448431
Salah Mahmoudi
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Elena Mancini
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Alessandra Moore
2Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University, Stanford, CA 94305, USA
Lucy Xu
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
3Department of Biology, Stanford University, Stanford, CA 94305, USA
Fereshteh Jahanbani
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Katja Hebestreit
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Rajini Srinivasan
4Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA
Xiyan Li
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Keerthana Devarajan
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Laurie Prélot
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Cheen Euong Ang
5Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
6Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
7Department of Pathology, Stanford University, Stanford, CA 94305, USA
Yohei Shibuya
5Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
7Department of Pathology, Stanford University, Stanford, CA 94305, USA
Bérénice A. Benayoun
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
8Current affiliation: Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA
Anne Lynn S. Chang
9Department of Dermatology, Stanford University, Stanford, CA 94305, USA
Marius Wernig
5Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
7Department of Pathology, Stanford University, Stanford, CA 94305, USA
Joanna Wysocka
3Department of Biology, Stanford University, Stanford, CA 94305, USA
5Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
Michael T. Longaker
2Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University, Stanford, CA 94305, USA
5Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
Michael P. Snyder
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Anne Brunet
1Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
10Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA 94305, USA
Posted October 19, 2018.
Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
Salah Mahmoudi, Elena Mancini, Alessandra Moore, Lucy Xu, Fereshteh Jahanbani, Katja Hebestreit, Rajini Srinivasan, Xiyan Li, Keerthana Devarajan, Laurie Prélot, Cheen Euong Ang, Yohei Shibuya, Bérénice A. Benayoun, Anne Lynn S. Chang, Marius Wernig, Joanna Wysocka, Michael T. Longaker, Michael P. Snyder, Anne Brunet
bioRxiv 448431; doi: https://doi.org/10.1101/448431
Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
Salah Mahmoudi, Elena Mancini, Alessandra Moore, Lucy Xu, Fereshteh Jahanbani, Katja Hebestreit, Rajini Srinivasan, Xiyan Li, Keerthana Devarajan, Laurie Prélot, Cheen Euong Ang, Yohei Shibuya, Bérénice A. Benayoun, Anne Lynn S. Chang, Marius Wernig, Joanna Wysocka, Michael T. Longaker, Michael P. Snyder, Anne Brunet
bioRxiv 448431; doi: https://doi.org/10.1101/448431
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