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Imaging Sterols and Oxysterols in Mouse Brain Reveals Distinct Spatial Cholesterol Metabolism

Eylan Yutuc, Roberto Angelini, Mark Baumert, Natalia Mast, Irina Pikuleva, Jillian Newton, Malcolm R. Clench, David O.F. Skibinski, Owain W. Howell, View ORCID ProfileYuqin Wang, View ORCID ProfileWilliam J. Griffiths
doi: https://doi.org/10.1101/450973
Eylan Yutuc
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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Roberto Angelini
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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Mark Baumert
Advion Limited, Harlow Enterprise Hub, Edinburgh Way, Harlow, Essex, CM20 2NQ, UK
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Natalia Mast
Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, USA
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Irina Pikuleva
Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, USA
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Jillian Newton
Centre for Mass Spectrometry Imaging, Biomolecular Research Centre, Sheffield Hallam University, Howard Street, Sheffield, S1 1WB, UK
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Malcolm R. Clench
Centre for Mass Spectrometry Imaging, Biomolecular Research Centre, Sheffield Hallam University, Howard Street, Sheffield, S1 1WB, UK
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David O.F. Skibinski
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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Owain W. Howell
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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Yuqin Wang
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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  • ORCID record for Yuqin Wang
  • For correspondence: w.j.griffiths@swansea.ac.uk
William J. Griffiths
Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
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  • ORCID record for William J. Griffiths
  • For correspondence: w.j.griffiths@swansea.ac.uk
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Article Information

doi 
https://doi.org/10.1101/450973
History 
  • October 13, 2019.

Article Versions

  • Version 1 (October 23, 2018 - 12:45).
  • Version 2 (May 8, 2019 - 22:14).
  • You are viewing Version 3, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Eylan Yutuc1,
  2. Roberto Angelini1,
  3. Mark Baumert2,
  4. Natalia Mast3,
  5. Irina Pikuleva3,
  6. Jillian Newton4,
  7. Malcolm R. Clench4,
  8. David O.F. Skibinski1,
  9. Owain W. Howell1,
  10. Yuqin Wang1,* and
  11. William J. Griffiths1,*
  1. 1Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, SA2 8PP, Wales, UK
  2. 2Advion Limited, Harlow Enterprise Hub, Edinburgh Way, Harlow, Essex, CM20 2NQ, UK
  3. 3Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, USA
  4. 4Centre for Mass Spectrometry Imaging, Biomolecular Research Centre, Sheffield Hallam University, Howard Street, Sheffield, S1 1WB, UK
  1. ↵*Corresponding authors. email: w.j.griffiths{at}swansea.ac.uk
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Posted October 13, 2019.
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Imaging Sterols and Oxysterols in Mouse Brain Reveals Distinct Spatial Cholesterol Metabolism
Eylan Yutuc, Roberto Angelini, Mark Baumert, Natalia Mast, Irina Pikuleva, Jillian Newton, Malcolm R. Clench, David O.F. Skibinski, Owain W. Howell, Yuqin Wang, William J. Griffiths
bioRxiv 450973; doi: https://doi.org/10.1101/450973
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Imaging Sterols and Oxysterols in Mouse Brain Reveals Distinct Spatial Cholesterol Metabolism
Eylan Yutuc, Roberto Angelini, Mark Baumert, Natalia Mast, Irina Pikuleva, Jillian Newton, Malcolm R. Clench, David O.F. Skibinski, Owain W. Howell, Yuqin Wang, William J. Griffiths
bioRxiv 450973; doi: https://doi.org/10.1101/450973

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