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ETDB-Caltech: a blockchain-based distributed public database for electron tomography

Davi R. Ortega, Catherine M. Oikonomou, H. Jane Ding, Prudence Rees-Lee, Alexandria, Grant J. Jensen
doi: https://doi.org/10.1101/453662
Davi R. Ortega
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Catherine M. Oikonomou
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA
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H. Jane Ding
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Prudence Rees-Lee
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Alexandria
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Grant J. Jensen
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA
2Howard Hughes Medical Institute, Pasadena, California, USA
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  • For correspondence: jensen@caltech.edu
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Abstract

Three-dimensional electron microscopy techniques like electron tomography provide valuable insights into cellular structures, and present significant challenges for data storage and dissemination. Here we explored a novel method to publicly release more than 11,000 such datasets, more than 30 TB in total, collected by our group. Our method, based on a peer-to-peer file sharing network built around a blockchain ledger, offers a distributed solution to data storage. In addition, we offer a user-friendly browser-based interface, https://etdb.caltech.edu, for anyone interested to explore and download our data. We discuss the relative advantages and disadvantages of this system and provide tools for other groups to mine our data and/or use the same approach to share their own imaging datasets.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
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Posted October 25, 2018.
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ETDB-Caltech: a blockchain-based distributed public database for electron tomography
Davi R. Ortega, Catherine M. Oikonomou, H. Jane Ding, Prudence Rees-Lee, Alexandria, Grant J. Jensen
bioRxiv 453662; doi: https://doi.org/10.1101/453662
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ETDB-Caltech: a blockchain-based distributed public database for electron tomography
Davi R. Ortega, Catherine M. Oikonomou, H. Jane Ding, Prudence Rees-Lee, Alexandria, Grant J. Jensen
bioRxiv 453662; doi: https://doi.org/10.1101/453662

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