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Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
View ORCID ProfileDaniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Munir Ahmad, Gema Vizcay-Barrena, Andrea Protti, Peter S. Zammit, Cristobal G. dos Remedios, Elisabeth Ehler, Ajay M. Shah, Catherine M. Shanahan
doi: https://doi.org/10.1101/457044
Daniel Brayson
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
PhDAndrea Frustaci
2Department of Cardiovascular, Nefrologic, Anestesiologic and Geriatric Sciences, La Sapienza University of Rome, Italy
3National Institute for Infectious Diseases IRCCS ‘L. Spallanzani’, Rome, Italy
MDRomina Verardo
3National Institute for Infectious Diseases IRCCS ‘L. Spallanzani’, Rome, Italy
PhDCristina Chimenti
2Department of Cardiovascular, Nefrologic, Anestesiologic and Geriatric Sciences, La Sapienza University of Rome, Italy
3National Institute for Infectious Diseases IRCCS ‘L. Spallanzani’, Rome, Italy
MD,PhDMatteo Antonio Russo
4MEBIC Open University San Raffaele and IRCCS San Raffaele Pisana, Laboratory of Molecular and Cellular Pathology, Milan, Italy
MDRobert Hayward
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
BScSadia Munir Ahmad
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
MScGema Vizcay-Barrena
5Centre for Ultrastructural Imaging, Guy’s Campus, King’s College London, London, UK
PhDAndrea Protti
6Department of Imaging, Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
PhDPeter S. Zammit
7Randall Centre for Cell and Molecular Biophysics, King’s College London, UK
PhDCristobal G. dos Remedios
8Department of Anatomy, Bosch Institute, University of Sydney, Sydney, NSW, Australia
PhDElisabeth Ehler
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
7Randall Centre for Cell and Molecular Biophysics, King’s College London, UK
PhDAjay M. Shah
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
MDCatherine M. Shanahan
1School of Cardiovascular Medicine and Sciences, King’s College London BHF Centre for Research Excellence, London, UK
PhD
Posted November 28, 2018.
Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Munir Ahmad, Gema Vizcay-Barrena, Andrea Protti, Peter S. Zammit, Cristobal G. dos Remedios, Elisabeth Ehler, Ajay M. Shah, Catherine M. Shanahan
bioRxiv 457044; doi: https://doi.org/10.1101/457044
Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Munir Ahmad, Gema Vizcay-Barrena, Andrea Protti, Peter S. Zammit, Cristobal G. dos Remedios, Elisabeth Ehler, Ajay M. Shah, Catherine M. Shanahan
bioRxiv 457044; doi: https://doi.org/10.1101/457044
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