New Results
Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways
Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R.I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas-de-Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Joel Gelernter, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M.J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A.M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Nadia Solovieff, Scott R. Sponheim, Dan J. Stein, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Keith A. Young, Ross McD. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen
doi: https://doi.org/10.1101/458562
Caroline M. Nievergelt
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego, CA, US.Veterans Affairs San Diego Healthcare System, Research Service, San Diego, CA, US
Adam X. Maihofer
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego, CA, US.Veterans Affairs San Diego Healthcare System, Research Service, San Diego, CA, US
Torsten Klengel
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Elizabeth G. Atkinson
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USMassachusetts General Hospital, Analytic and Translational Genetics Unit, Boston, MA, US
Chia-Yen Chen
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USMassachusetts General Hospital, Analytic and Translational Genetics Unit, Boston, MA, USMassachusetts General Hospital, Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Boston, MA, US
Karmel W. Choi
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USHarvard T.H, Chan School of Public Health, Department of Epidemiology, Boston, MA, USMassachusetts General Hospital, Department of Psychiatry, Boston, MA, US
Jonathan R.I. Coleman
King’s College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, GBKing’s College London, NIHR BRC at the Maudsley, London, GB
Shareefa Dalvie
University of Cape Town, SA MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, Cape Town, Western Cape, ZA.
Laramie E. Duncan
Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, CA, US
Mark W. Logue
VA Boston Healthcare System, National Center for PTSD, Boston, MA, US
Allison C. Provost
Cohen Veterans Bioscience, Cambridge, MA, US.
Andrew Ratanatharathorn
TH Chan School of Public Health, Department of Epidemiology, Boston, MA, US
Murray B. Stein
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Psychiatry Service, San Diego, CA, US
Katy Torres
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego, CA, US.Veterans Affairs San Diego Healthcare System, Research Service, San Diego, CA, US
Allison E. Aiello
University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, NC, US
Lynn M. Almli
Carter Consulting, Atlanta, GA, US
Ananda B. Amstadter
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Richmond, VA, US
Søren B Andersen
The Danish Veteran Centre, Research and Knowledge Centre, Ringsted, Sjaelland, DK
Ole A. Andreassen
University of Oslo, Institute of Clinical Medicine, Oslo, NO.
Paul A. Arbisi
Minneapolis VA Health Care System, Mental Health Service Line, Minneapolis, MN, US.
Allison E. Ashley-Koch
Duke University, Department of Psychiatry, Durham, NC, US.
S. Bryn Austin
Boston Children’s Hospital, Division of Adolescent and Young Adult Medicine, Boston, MA, US.Brigham and Women’s Hospital, Channing Division of Network Medicine, Boston, MA, US.Harvard Medical School, Department of Psychiatry, Boston, MA, USHarvard School of Public Health, Department of Social and Behavioral Sciences, Boston, MA, US.
Esmina Avdibegovic
University Clinical Center of Tuzla, Department of Psychiatry, Tuzla, BA.
Dragan Babić
University Clinical Center of Mostar, Department of Psychiatry, Mostar, BA.
Marie Bækvad-Hansen
Statens Serum Institut, Department for Congenital Disorders, Copenhagen, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Dewleen G. Baker
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego, CA, US.Veterans Affairs San Diego Healthcare System, Psychiatry Service, San Diego, CA, US
Jean C. Beckham
Duke University, Department of Psychiatry and Behavioral Sciences, Durham, NC, US.Durham VA Medical Center, Research, Durham, NC, US.VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), Genetics Research Laboratory, Durham, NC, US.
Laura J. Bierut
Washington University in Saint Louis School of Medicine, Department of Psychiatry, Saint Louis, MO, US.
Jonathan I. Bisson
Cardiff University, National Centre for Mental Health, MRC Centre for Psychiatric Genetics and Genomics, Cardiff, South Glamorgan, GB.
Marco P. Boks
UMC Utrecht Brain Center Rudolf Magnus, Department of Translational Neuroscience, Utrecht, Utrecht, NL.
Elizabeth A. Bolger
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Anders D. Børglum
Aarhus University, Centre for Integrative Sequencing, iSEQ, Aarhus, DK.Aarhus University, Department of Biomedicine - Human Genetics, Aarhus, DKThe Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Bekh Bradley
Atlanta VA Health Care System, Mental Health Service Line, Decatur, GA, US.Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Megan Brashear
Louisiana State University Health Sciences Center, School of Public Health and Department of Epidemiology, New Orleans, LA, US.
Gerome Breen
King’s College London, NIHR BRC at the Maudsley, London, GBKing’s College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, GB
Richard A. Bryant
University of New South Wales, Department of Psychology, Sydney, NSW, AU.
Angela C. Bustamante
University of Michigan Medical School, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, Mi, US.
Jonas Bybjerg-Grauholm
Statens Serum Institut, Department for Congenital Disorders, Copenhagen, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Joseph R. Calabrese
University Hospitals, Department of Psychiatry, Cleveland, OH, US.
José M. Caldas-de-Almeida
CEDOC -Chronic Diseases Research Centre, Lisbon Institute of Global Mental Health, Lisbon, PT.
Anders M. Dale
Unversity of California, San Diego, Department of Radiology, Department of Neurosciences, La Jolla, CA, US.
Mark J. Daly
Massachusetts General Hospital, Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Boston, MA, US
Nikolaos P. Daskalakis
Cohen Veterans Bioscience, Cambridge, MA, US.Harvard Medical School, Department of Psychiatry, Boston, MA, USIcahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, US.McLean Hospital, Belmont, MA, US
Jürgen Deckert
University Hospital of Würzburg, Center of Mental Health, Psychiatry, Psychosomatics and Psychotherapy, Würzburg, DE.
Douglas L. Delahanty
Kent State University, Department of Psychological Sciences, Kent, OH, US.Kent State University, Research and Sponsored Programs, Kent, OH, US.
Michelle F. Dennis
Duke University, Duke Molecular Physiology Institute, Durham, NC, US.Durham VA Medical Center, Research, Durham, NC, US.
Seth G. Disner
Minneapolis VA Health Care System, Research Service Line, Minneapolis, MN, US.
Katharina Domschke
Medical Center-University of Freiburg, Faculty of Medicine, Department of Psychiatry and Psychotherapy, Freiburg, DE.
Alma Dzubur-Kulenovic
University Clinical Center of Sarajevo, Department of Psychiatry, Sarajevo, BA.
Christopher R. Erbes
Minneapolis VA Health Care System, Center for Care Delivery and Outcomes Research (CCDOR), Minneapolis, MN, US.University of Minnesota, Department of Psychiatry, Minneapolis, MN, US.
Alexandra Evans
Cardiff University, National Centre for Mental Health, MRC Centre for Psychiatric Genetics and Genomics, Cardiff, South Glamorgan, GB.
Lindsay A. Farrer
Boston University School of Medicine, Department of Medicine, Boston, MA, US.
Norah C. Feeny
Case Western Reserve University, Department of Psychological Sciences, Cleveland, OH, US.
Janine D. Flory
Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, US.
David Forbes
University of Melbourne, Department of Psychiatry, Melbourne, VIC, AU.
Carol E. Franz
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.
Sandro Galea
Boston University, Department of Psychological and Brain Sciences, Boston, MA, US.
Melanie E. Garrett
Duke University, Department of Psychiatry and Behavioral Sciences, Durham, NC, US.
Bizu Gelaye
Harvard T.H, Chan School of Public Health, Department of Epidemiology, Boston, MA, US
Joel Gelernter
US Department of Veterans Affairs, Department of Psychiatry, West Haven, CT, US.Yale University School of Medicine, Department of Genetics and Neuroscience, New Haven, CT, US.
Elbert Geuze
Netherlands Ministry of Defence, Research Center Military Mental Healthcare, Utrecht, Utrecht, NL.UMC Utrecht Brain Center Rudolf Magnus, Department of Psychiatry, Utrecht, Utrecht, NL.
Charles Gillespie
Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Aferdita Goci Uka
University Clinical Centre of Kosovo, Department of Psychiatry, Prishtina, Kosovo, XK.
Scott D. Gordon
QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Queensland, AU.
Guia Guffanti
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Rasha Hammamieh
US Army Medical Research and Materiel Command, USACEHR, Fort Detrick, MD, US.
Supriya Harnal
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, US.
Michael A. Hauser
Duke University, Department of Psychiatry and Behavioral Sciences, Durham, NC, US.
Andrew C. Heath
Washington University in Saint Louis School of Medicine, Department of Genetics, Saint Louis, MO, US.
Sian M.J. Hemmings
Stellenbosch University Faculty of Medicine and Health Sciences, Department of Psychiatry, Cape Town, Western Cape, ZA.
David Michael Hougaard
Statens Serum Institut, Department for Congenital Disorders, Copenhagen, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Miro Jakovljevic
University Hospital Center of Zagreb, Department of Psychiatry, Zagreb, HR.
Marti Jett
US Army Medical Research and Materiel Command, USACEHR, Fort Detrick, MD, US.
Eric Otto Johnson
RTI International, Behavioral Health and Criminal Justice Division, Research Triangle Park, NC, US.
Ian Jones
Cardiff University, National Centre for Mental Health, MRC Centre for Psychiatric Genetics and Genomics, Cardiff, South Glamorgan, GB.
Tanja Jovanovic
Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Xue-Jun Qin
Duke University, Duke Molecular Physiology Institute, Durham, NC, US.
Angela G. Junglen
Kent State University, Department of Pschological Sciences, Kent, OH, US.
Karen-Inge Karstoft
The Danish Veteran Center, Research and Knowledge Centre, Ringsted, Zealand, DK.University of Copenhagen, Department of Psychology, Copenhagen, DK.
Milissa L. Kaufman
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Ronald C. Kessler
Harvard Medical School, Department of Psychiatry, Boston, MA, US
Alaptagin Khan
Harvard Medical School, Department of Health Care Policy, Boston, MA, US.McLean Hospital, Belmont, MA, US
Nathan A. Kimbrel
Duke University, Duke Molecular Physiology Institute, Durham, NC, US.Durham VA Medical Center, Research, Durham, NC, US.VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), Genetics Research Laboratory, Durham, North Carolina, US.
Anthony P. King
University of Michigan Medical School, Department of Psychiatry, Ann Arbor, MI, US.
Nastassja Koen
University of Cape Town, SA MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, Cape Town, Observatory, Western Cape, ZA.
Henry R. Kranzler
University of Pennsylvania Perelman School of Medicine, Department of Psychiatry, Philadelphia, PA, US.
William S. Kremen
University of California San Diego, Department of Psychiatry and Department of Family Medicine and Public Health, La Jolla, CA, US.
Bruce R. Lawford
Queensland University of Technology, IHBI, Brisbane, QLD, AU.Queensland University of Technology, School of Biomedical Sciences, Brisbane, QLD, AU.
Lauren A.M. Lebois
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Catrin E. Lewis
Cardiff University, National Centre for Mental Health, MRC Centre for Psychiatric Genetics and Genomics, Cardiff, South Glamorgan, GB.
Sarah D. Linnstaedt
UNC Institute for Trauma Recovery, Department of Anesthesiology, Chapel Hill, NC, US.
Adriana Lori
Emory University, Department of Gynecology and Obstetrics, Atlanta, GA, US.
Bozo Lugonja
Cardiff University, National Centre for Mental Health, MRC Centre for Psychiatric Genetics and Genomics, Cardiff, South Glamorgan, GB.
Jurjen J. Luykx
UMC Utrecht Brain Center Rudolf Magnus, Department of Psychiatry, Utrecht, Utrecht, NL.UMC Utrecht Brain Center Rudolf Magnus, Department of Translational Neuroscience, Utrecht, Utrecht, NL.
Michael J. Lyons
Boston University, Dean’s Office, Boston, MA, US.
Jessica Maples-Keller
Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Charles Marmar
New York University, Department of Psychiatry, New York, NY, US.
Alicia R. Martin
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USMassachusetts General Hospital, Analytic and Translational Genetics Unit, Boston, MA, US
Nicholas G. Martin
QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Queensland, AU.
Douglas Maurer
United States Army, Command, Fort Sill, OK, US.
Matig R. Mavissakalian
University Hospitals, Department of Psychiatry, Cleveland, OH, US.
Alexander McFarlane
University of Adelaide, Department of Psychiatry, Adelaide, South Australia, AU.
Regina E. McGlinchey
VA Boston Health Care System, GRECC/TRACTS, Boston, MA, US.
Katie A. McLaughlin
Harvard University, Department of Psychology, Boston, MA, US.
Samuel A. McLean
UNC Institute for Trauma Recovery, Department of Anesthesiology, Chapel Hill, NC, US.UNC Institute for Trauma Recovery, Department of Emergency Medicine, Chapel Hill, NC, US.
Sarah McLeay
Gallipoli Medical Research Institute, PTSD Initiative, Greenslopes, Queensland, AU.
Divya Mehta
Queensland University of Technology, Faculty of Health, Brisbane, QLD, AU.
William P. Milberg
VA Boston Health Care System, GRECC/TRACTS, Boston, MA, US.
Mark W. Miller
VA Boston Healthcare System, National Center for PTSD, Boston, MA, US
Rajendra A. Morey
Duke University, Duke Molecular Physiology Institute, Durham, NC, US.
Charles Phillip Morris
Queensland University of Technology, Faculty of Health, Brisbane, QLD, AU.
Ole Mors
Aarhus University Hospital, Psychosis Research Unit, Risskov, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Preben B. Mortensen
Aarhus University, Centre for Integrated Register-based Research, Aarhus, DK.Aarhus University, Centre for Integrative Sequencing, iSEQ, Aarhus, DK.Aarhus University, National Centre for Register-Based Research, Aarhus, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Benjamin M. Neale
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USMassachusetts General Hospital, Analytic and Translational Genetics Unit, Boston, MA, US
Elliot C. Nelson
Washington University in Saint Louis School of Medicine, Department of Psychiatry, Saint Louis, MO, US.
Merete Nordentoft
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.University of Copenhagen, Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, Copenhagen, DK.
Sonya B. Norman
National Center for Post Traumatic Stress Disorder, Executive Division, White River Junction, VT, US.University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Department of Research and Psychiatry, San Diego, CA, US.
Meaghan O’Donnell
University of Melbourne, Department of Psychiatry, Melbourne, VIC, AU.
Holly K. Orcutt
Northern Illinois University, Department of Psychology, DeKalb, IL, US.
Matthew S. Panizzon
University of California San Diego, Department of Psychiatry, La Jolla, California, US.
Edward S. Peters
Louisiana State University Health Sciences Center, School of Public Health and Department of Epidemiology, New Orleans, LA, US.
Alan L. Peterson
University of Texas San Antonio, Department of Psychology, San Antonio, TX, US.
Matthew Peverill
University of Washington, Department of Psychology, Seattle, WA, US.
Robert H. Pietrzak
U.S, Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, West Haven, CT, US.Yale University School of Medicine, Department of Psychiatry, New Haven, CT, US.
Melissa A. Polusny
Minneapolis VA Health Care System, Department of Mental Health, Minneapolis, MN, US.Minneapolis VA Health Care System, Department of Psychology, Minneapolis, MN, US.University of Minnesota System, Department of Psychiatry, Minneapolis, MN, US.
John P. Rice
Washington University in Saint Louis School of Medicine, Department of Psychiatry, Saint Louis, MO, US.
Stephan Ripke
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, US.Charité - Universitätsmedizin, Department of Psychiatry and Psychotherapy, Berlin, GE.Massachusetts General Hospital, Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Boston, MA, US
Victoria B. Risbrough
University of California San Diego, Department of Psychiatry, La Jolla, CA, US.Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego, CA, US.Veterans Affairs San Diego Healthcare System, Research Service, San Diego, CA, US
Andrea L. Roberts
Harvard T.H, Chan School of Public Health, Department of Environmental Health, Boston, MA, US.
Alex O. Rothbaum
Case Western Reserve University, Department of Psychological Sciences, Cleveland, OH, US.
Barbara O. Rothbaum
Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Peter Roy-Byrne
University of Washington, Department of Psychology, Seattle, WA, US.
Ken Ruggiero
Medical University of South Carolina, Department of Nursing and Department of Psychiatry, Charleston, SC, US.
Ariane Rung
Louisiana State University Health Sciences Center, School of Medicine and Department of Physiology, New Orleans, LA, US.
Bart P. F. Rutten
Maastricht Universitair Medisch Centrum, School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Maastricht, Limburg, NL.
Nancy L. Saccone
Washington University in Saint Louis School of Medicine, Department of Psychiatry, Saint Louis, MO, US.
Sixto E. Sanchez
Universidad Peruana de Ciencias Aplicadas Facultad de Ciencias de la Salud, Department of Medicine, Lima, Lima, PE.
Dick Schijven
UMC Utrecht Brain Center Rudolf Magnus, Department of Psychiatry, Utrecht, Utrecht, NL.UMC Utrecht Brain Center Rudolf Magnus, Department of Translational Neuroscience, Utrecht, Utrecht, NL.
Soraya Seedat
Stellenbosch University Faculty of Medicine and Health Sciences, Department of Psychiatry, Cape Town, Western Cape, ZA.
Antonia V. Seligowski
Harvard Medical School, Department of Pediatrics, Boston, MA, US.McLean Hospital, Belmont, MA, US
Julia S. Seng
University of Michigan, School of Nursing, Ann Arbor, Michigan, US.
Christina M. Sheerin
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Richmond, VA, US
Derrick Silove
University of New South Wales, Department of Psychiatry, Sydney, NSW, AU.
Alicia K. Smith
Emory University, Department of Gynecology and Obstetrics, Atlanta, GA, US.Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.
Jordan W. Smoller
Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USMassachusetts General Hospital, Analytic and Translational Genetics Unit, Boston, MA, USMassachusetts General Hospital, Department of Psychiatry, Boston, MA, US
Nadia Solovieff
Massachusetts General Hospital, Boston, MA, US.
Scott R. Sponheim
Minneapolis VA Health Care System, Mental Health Service Line, Minneapolis, MN, US.University of Minnesota, Department of Psychiatry, Minneapolis, MN, US.
Dan J. Stein
University of Cape Town, SA MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, Cape Town, ZA.
Jennifer A. Sumner
Columbia University Medical Center, Department of Medicine, New York, NY, US.
Martin H. Teicher
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Wesley K. Thompson
Mental Health Centre Sct, Hans, Institute of Biological Psychiatry, Roskilde, DK.Oslo University Hospital, KG Jebsen Centre for Psychosis Research, Norway Division of Mental Health and Addiction, Oslo, NO.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.University of California San Diego, Department of Psychiatry, La Jolla, CA, US.
Edward Trapido
Louisiana State University Health Sciences Center, School of Public Health and Department of Epidemiology, New Orleans, LA, US.
Monica Uddin
University of Illinois at Urbana-Champaign, Carl R, Woese Institute for Genomic Biology, Urbana, IL, US.University of Illinois at Urbana-Champaign, Department of Psychology, Urbana, IL, US.
Robert J. Ursano
Uniformed Services University, Department of Psychiatry, Bethesda, Maryland, US.
Leigh Luella van den Heuvel
Stellenbosch University Faculty of Medicine and Health Sciences, Department of Psychiatry, Cape Town, Western Cape, ZA.
Miranda van Hooff
University of Adelaide, Department of Psychiatry, Adelaide, South Australia, AU.
Eric Vermetten
Arq, Psychotrauma Reseach Expert Group, Diemen, NH, NL.Leiden University Medical Center, Department of Psychiatry, Leiden, ZH, NL.Netherlands Defense Department, Research Center, Utrecht, UT, NL.New York University School of Medicine, Department of Psychiatry, New York, NY, US.
Christiaan H. Vinkers
Amsterdam UMC (location VUmc), Department of Anatomy and Neurosciences, Amsterdam Holland, NL.Amsterdam UMC (location VUmc), Department of Psychiatry, Amsterdam, Holland, NL.
Joanne Voisey
Queensland University of Technology, IHBI, Brisbane, QLD, AU.
Yunpeng Wang
Mental Health Centre Sct, Hans, Institute of Biological Psychiatry, Roskilde, DK.Oslo University Hospital, KG Jebsen Centre for Psychosis Research, Norway Division of Mental Health and Addiction, Oslo, NO.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.
Zhewu Wang
Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, US.Ralph H Johnson VA Medical Center, Department of Mental Health, Charleston, SC, US.
Thomas Werge
Mental Health Centre Sct, Hans, Institute of Biological Psychiatry, Roskilde, DK.The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, DK.University of Copenhagen, Department of Clinical Medicine, Copenhagen, DK.
Michelle A. Williams
Harvard T.H, Chan School of Public Health, Department of Epidemiology, Boston, MA, US
Douglas E. Williamson
Duke University, Department of Psychiatry and Behavioral Sciences, Durham, NC, US.Durham VA Medical Center, Mental Health Service Line, Durham, NC, US.
Sherry Winternitz
Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Christiane Wolf
University Hospital of Würzburg, Center of Mental Health, Psychiatry, Psychosomatics and Psychotherapy, Würzburg, DE.
Erika J. Wolf
VA Boston Healthcare System, National Center for PTSD, Boston, MA, US
Jonathan D. Wolff
McLean Hospital, Belmont, MA, US
Rachel Yehuda
Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, US.James J Peters VA Medical Center, Department of Mental Health, Bronx, NY, US
Keith A. Young
Baylor Scott and White Central Texas, Department of Psychiatry, Temple, TX, US.CTVHCS, Psychiatry Research, Temple, TX, US.
Ross McD. Young
Queensland University of Technology, School of Psychology and Counseling, Brisbane, QLD, AU.
Hongyu Zhao
Yale University, Department of Biostatistics, New Haven, CT, US.
Lori A. Zoellner
University of Washington, Department of Psychiatry and Behavioral Sciences, Seattle, WA, US.
Israel Liberzon
University of Michigan Medical School, Department of Psychiatry, Ann Arbor, MI, US.
Kerry J. Ressler
Emory University, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, US.Harvard Medical School, Department of Psychiatry, Boston, MA, USMcLean Hospital, Belmont, MA, US
Magali Haas
Cohen Veterans Bioscience, Cambridge, MA, US.
Karestan C. Koenen
Harvard School of Public Health, Department of Epidemiology, Boston, MA, US.
Article usage
Posted November 01, 2018.
Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways
Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R.I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas-de-Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Joel Gelernter, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M.J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A.M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Nadia Solovieff, Scott R. Sponheim, Dan J. Stein, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Keith A. Young, Ross McD. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen
bioRxiv 458562; doi: https://doi.org/10.1101/458562
Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways
Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R.I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas-de-Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Joel Gelernter, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M.J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A.M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Nadia Solovieff, Scott R. Sponheim, Dan J. Stein, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Keith A. Young, Ross McD. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen
bioRxiv 458562; doi: https://doi.org/10.1101/458562
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