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Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
Matthew Simon, Michael Van Meter, Julia Ablaeva, Zhonghe Ke, Raul S. Gonzalez, Taketo Taguchi, Marco De Cecco, Katerina I. Leonova, Valeria Kogan, Stephen L. Helfand, Nicola Neretti, Asael Roichman, Haim Y. Cohen, Marina Antoch, Andrei Gudkov, John M. Sedivy, Andrei Seluanov, Vera Gorbunova
doi: https://doi.org/10.1101/460808
Matthew Simon
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Michael Van Meter
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Julia Ablaeva
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Zhonghe Ke
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Raul S. Gonzalez
2Department of Pathology, University of Rochester Medical Center, Rochester, New York 14627, USA
Taketo Taguchi
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Marco De Cecco
4Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912, USA
Katerina I. Leonova
3Department of Cell Stress Biology, CGP 3310, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Valeria Kogan
3Department of Cell Stress Biology, CGP 3310, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Stephen L. Helfand
4Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912, USA
Nicola Neretti
4Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912, USA
Asael Roichman
5Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel
Haim Y. Cohen
5Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel
Marina Antoch
3Department of Cell Stress Biology, CGP 3310, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Andrei Gudkov
3Department of Cell Stress Biology, CGP 3310, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
John M. Sedivy
4Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912, USA
Andrei Seluanov
1Department of Biology, University of Rochester, Rochester, New York 14627, USA
Vera Gorbunova
1Department of Biology, University of Rochester, Rochester, New York 14627, USA

Article Information
History
- November 4, 2018.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Posted November 04, 2018.
Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
Matthew Simon, Michael Van Meter, Julia Ablaeva, Zhonghe Ke, Raul S. Gonzalez, Taketo Taguchi, Marco De Cecco, Katerina I. Leonova, Valeria Kogan, Stephen L. Helfand, Nicola Neretti, Asael Roichman, Haim Y. Cohen, Marina Antoch, Andrei Gudkov, John M. Sedivy, Andrei Seluanov, Vera Gorbunova
bioRxiv 460808; doi: https://doi.org/10.1101/460808
Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
Matthew Simon, Michael Van Meter, Julia Ablaeva, Zhonghe Ke, Raul S. Gonzalez, Taketo Taguchi, Marco De Cecco, Katerina I. Leonova, Valeria Kogan, Stephen L. Helfand, Nicola Neretti, Asael Roichman, Haim Y. Cohen, Marina Antoch, Andrei Gudkov, John M. Sedivy, Andrei Seluanov, Vera Gorbunova
bioRxiv 460808; doi: https://doi.org/10.1101/460808
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