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BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
Maxime Sartori, Tiago Mendes, Shruti Desai, Alessia Lasorsa, Adrien Herledan, Nicolas Malmanche, Petra Mäkinen, Mikael Marttinen, Idir Malki, Julien Chapuis, Amandine Flaig, Anaïs-Camille Vreulx, Philippe Amouyel, Florence Leroux, Benoit Déprez, François-Xavier Cantrelle, Damien Maréchal, Laurent Pradier, Mikko Hiltunen, Isabelle Landrieu, Devrim Kilinc, Yann Herault, Jocelyn Laporte, View ORCID ProfileJean-Charles Lambert
doi: https://doi.org/10.1101/462317
Maxime Sartori
1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France
2INSERM U1258, Illkirch, France
3CNRS UMR7104, Illkirch, France
4Strasbourg University, Illkirch, France
Tiago Mendes
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
8SANOFI Neuroscience Therapeutic Area, Chilly-Mazarin, France
Shruti Desai
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Alessia Lasorsa
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
9CNRS UMR8576, Lille, France
Adrien Herledan
6Institut Pasteur de Lille, Lille, France
10University of Lille, EGID, Lille, France
11INSERM U1177, Drugs and Molecules for Living Systems, Lille, France
Nicolas Malmanche
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Petra Mäkinen
12Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
Mikael Marttinen
12Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
Idir Malki
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
9CNRS UMR8576, Lille, France
Julien Chapuis
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Amandine Flaig
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Anaïs-Camille Vreulx
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Philippe Amouyel
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Florence Leroux
6Institut Pasteur de Lille, Lille, France
10University of Lille, EGID, Lille, France
11INSERM U1177, Drugs and Molecules for Living Systems, Lille, France
Benoit Déprez
6Institut Pasteur de Lille, Lille, France
10University of Lille, EGID, Lille, France
11INSERM U1177, Drugs and Molecules for Living Systems, Lille, France
François-Xavier Cantrelle
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
9CNRS UMR8576, Lille, France
Damien Maréchal
1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France
2INSERM U1258, Illkirch, France
3CNRS UMR7104, Illkirch, France
4Strasbourg University, Illkirch, France
Laurent Pradier
8SANOFI Neuroscience Therapeutic Area, Chilly-Mazarin, France
Mikko Hiltunen
12Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
Isabelle Landrieu
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
9CNRS UMR8576, Lille, France
Devrim Kilinc
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Yann Herault
1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France
2INSERM U1258, Illkirch, France
3CNRS UMR7104, Illkirch, France
4Strasbourg University, Illkirch, France
Jocelyn Laporte
1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France
2INSERM U1258, Illkirch, France
3CNRS UMR7104, Illkirch, France
4Strasbourg University, Illkirch, France
Jean-Charles Lambert
5INSERM U1167, RID-AGE: Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
6Institut Pasteur de Lille, Lille, France
7University of Lille, DISTALZ Laboratory of Excellence (LabEx), Lille, France
Article usage
Posted November 08, 2018.
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
Maxime Sartori, Tiago Mendes, Shruti Desai, Alessia Lasorsa, Adrien Herledan, Nicolas Malmanche, Petra Mäkinen, Mikael Marttinen, Idir Malki, Julien Chapuis, Amandine Flaig, Anaïs-Camille Vreulx, Philippe Amouyel, Florence Leroux, Benoit Déprez, François-Xavier Cantrelle, Damien Maréchal, Laurent Pradier, Mikko Hiltunen, Isabelle Landrieu, Devrim Kilinc, Yann Herault, Jocelyn Laporte, Jean-Charles Lambert
bioRxiv 462317; doi: https://doi.org/10.1101/462317
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
Maxime Sartori, Tiago Mendes, Shruti Desai, Alessia Lasorsa, Adrien Herledan, Nicolas Malmanche, Petra Mäkinen, Mikael Marttinen, Idir Malki, Julien Chapuis, Amandine Flaig, Anaïs-Camille Vreulx, Philippe Amouyel, Florence Leroux, Benoit Déprez, François-Xavier Cantrelle, Damien Maréchal, Laurent Pradier, Mikko Hiltunen, Isabelle Landrieu, Devrim Kilinc, Yann Herault, Jocelyn Laporte, Jean-Charles Lambert
bioRxiv 462317; doi: https://doi.org/10.1101/462317
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