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OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
Ranjie Xu, Andrew T Brawner, Shenglan Li, JingJing Liu, Hyosung Kim, Haipeng Xue, Zhiping P. Pang, Woo-Yang Kim, Ronald P. Hart, Ying Liu, View ORCID ProfilePeng Jiang
doi: https://doi.org/10.1101/462739
Ranjie Xu
1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
2Department of Developmental Neuroscience, Munroe-Meyer Institute and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA
Andrew T Brawner
2Department of Developmental Neuroscience, Munroe-Meyer Institute and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA
Shenglan Li
3Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
JingJing Liu
4Department of Neuroscience and Cell Biology and Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
Hyosung Kim
1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
Haipeng Xue
3Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Zhiping P. Pang
4Department of Neuroscience and Cell Biology and Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
Woo-Yang Kim
5Biological Sciences, Kent State University, Kent, OH 44242, USA
Ronald P. Hart
1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
Ying Liu
3Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Peng Jiang
1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
2Department of Developmental Neuroscience, Munroe-Meyer Institute and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA
Posted May 07, 2019.
OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
Ranjie Xu, Andrew T Brawner, Shenglan Li, JingJing Liu, Hyosung Kim, Haipeng Xue, Zhiping P. Pang, Woo-Yang Kim, Ronald P. Hart, Ying Liu, Peng Jiang
bioRxiv 462739; doi: https://doi.org/10.1101/462739
OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
Ranjie Xu, Andrew T Brawner, Shenglan Li, JingJing Liu, Hyosung Kim, Haipeng Xue, Zhiping P. Pang, Woo-Yang Kim, Ronald P. Hart, Ying Liu, Peng Jiang
bioRxiv 462739; doi: https://doi.org/10.1101/462739
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