Proteostasis environment shapes higher-order epistasis operating on antibiotic resistance

Rafael F. Guerrero; Samuel V. Scarpino; João V. Rodrigues; Daniel L. Hartl; C. Brandon Ogbunugafor

doi:10.1101/470971

Article Information

doi

https://doi.org/10.1101/470971

History

November 16, 2018.

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

Rafael F. Guerrero*,
Samuel V. Scarpino†,
João V. Rodrigues‡,
Daniel L. Hartl§ and
C. Brandon Ogbunugafor**,††,‡‡

^*Department of Computer Science, Indiana University
^†Network Science Institute, Department of Marine and Environmental Sciences, and Department of Physics, Northeastern University
^‡Department of Chemistry and Chemical Biology, Harvard University
^§Department of Organismic and Evolutionary Biology, Harvard University
^**Department Ecology and Evolutionary Biology, Brown University
^††Department of Biology, University of Vermont
^‡‡Vermont Complex Systems Center, University of Vermont