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Disorganization of the histone core promotes organization of heterochromatin into phase-separated droplets

S. Sanulli, MJ. Trnka, V. Dharmarajan, RW. Tibble, BD. Pascal, A. Burlingame, PR. Griffin, JD. Gross, GJ. Narlikar
doi: https://doi.org/10.1101/473132
S. Sanulli
1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
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MJ. Trnka
1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
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V. Dharmarajan
2Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA
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RW. Tibble
1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
3Program in Chemistry and Chemical Biology, University of California San Francisco, San Francisco, CA 94158, USA
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BD. Pascal
2Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA
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A. Burlingame
1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
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PR. Griffin
2Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA
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JD. Gross
1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
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  • For correspondence: jdgross@cgl.ucsf.edu geeta.narlikar@ucsf.edu
GJ. Narlikar
4Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
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  • For correspondence: jdgross@cgl.ucsf.edu geeta.narlikar@ucsf.edu
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Article Information

doi 
https://doi.org/10.1101/473132
History 
  • November 18, 2018.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. S. Sanulli1,
  2. MJ. Trnka1,
  3. V. Dharmarajan2,
  4. RW. Tibble1,3,
  5. BD. Pascal2,
  6. A. Burlingame1,
  7. PR. Griffin2,
  8. JD. Gross1,* and
  9. GJ. Narlikar4,*
  1. 1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA
  2. 2Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA
  3. 3Program in Chemistry and Chemical Biology, University of California San Francisco, San Francisco, CA 94158, USA
  4. 4Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
  1. ↵*Corresponding author. Email: jdgross{at}cgl.ucsf.edu (JDG); geeta.narlikar{at}ucsf.edu (GJN)
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Posted November 18, 2018.
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Disorganization of the histone core promotes organization of heterochromatin into phase-separated droplets
S. Sanulli, MJ. Trnka, V. Dharmarajan, RW. Tibble, BD. Pascal, A. Burlingame, PR. Griffin, JD. Gross, GJ. Narlikar
bioRxiv 473132; doi: https://doi.org/10.1101/473132
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Disorganization of the histone core promotes organization of heterochromatin into phase-separated droplets
S. Sanulli, MJ. Trnka, V. Dharmarajan, RW. Tibble, BD. Pascal, A. Burlingame, PR. Griffin, JD. Gross, GJ. Narlikar
bioRxiv 473132; doi: https://doi.org/10.1101/473132

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