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Ezh2-dependent epigenetic reprogramming controls a developmental switch between modes of gastric neuromuscular regulation
Sabriya A. Syed, Yujiro Hayashi, Jeong-Heon Lee, Huihuang Yan, Andrea Lorincz, Peter R. Strege, Gabriella B. Gajdos, Srdjan Milosavljevic, Jinfu Nie, Jüri J. Rumessen, Simon J. Gibbons, Viktor J. Horvath, Michael R. Bardsley, Doug D. Redelman, Sabine Klein, Dieter Saur, Gianrico Farrugia, Zhiguo Zhang, Raul A. Urrutia, Tamas Ordog
doi: https://doi.org/10.1101/486423
Sabriya A. Syed
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
3Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Yujiro Hayashi
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Jeong-Heon Lee
3Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA, 55905
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
Huihuang Yan
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
5Division of Biomedical Statistics and Bioinformatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA, 55905
Andrea Lorincz
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Peter R. Strege
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
Gabriella B. Gajdos
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Srdjan Milosavljevic
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Jinfu Nie
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
5Division of Biomedical Statistics and Bioinformatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA, 55905
Jüri J. Rumessen
6QD-Research Unit and Department of Pathology and Gastroenterology C, Herlev and Gentofte Hospital, Hellerup, Denmark, 2900
Simon J. Gibbons
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
Viktor J. Horvath
7Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, USA, 89557
Michael R. Bardsley
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
Doug D. Redelman
7Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, USA, 89557
Sabine Klein
8Department of Internal Medicine 2, Klinikum rechts der Isar, Technische Universität München, München, Germany, 80333
Dieter Saur
8Department of Internal Medicine 2, Klinikum rechts der Isar, Technische Universität München, München, Germany, 80333
Gianrico Farrugia
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
Zhiguo Zhang
3Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA, 55905
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
Raul A. Urrutia
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
Tamas Ordog
1Enteric NeuroScience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA, 55905
2Gastroenterology Research Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA, 55905
4Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA, 55905
Article usage
Posted December 04, 2018.
Ezh2-dependent epigenetic reprogramming controls a developmental switch between modes of gastric neuromuscular regulation
Sabriya A. Syed, Yujiro Hayashi, Jeong-Heon Lee, Huihuang Yan, Andrea Lorincz, Peter R. Strege, Gabriella B. Gajdos, Srdjan Milosavljevic, Jinfu Nie, Jüri J. Rumessen, Simon J. Gibbons, Viktor J. Horvath, Michael R. Bardsley, Doug D. Redelman, Sabine Klein, Dieter Saur, Gianrico Farrugia, Zhiguo Zhang, Raul A. Urrutia, Tamas Ordog
bioRxiv 486423; doi: https://doi.org/10.1101/486423
Ezh2-dependent epigenetic reprogramming controls a developmental switch between modes of gastric neuromuscular regulation
Sabriya A. Syed, Yujiro Hayashi, Jeong-Heon Lee, Huihuang Yan, Andrea Lorincz, Peter R. Strege, Gabriella B. Gajdos, Srdjan Milosavljevic, Jinfu Nie, Jüri J. Rumessen, Simon J. Gibbons, Viktor J. Horvath, Michael R. Bardsley, Doug D. Redelman, Sabine Klein, Dieter Saur, Gianrico Farrugia, Zhiguo Zhang, Raul A. Urrutia, Tamas Ordog
bioRxiv 486423; doi: https://doi.org/10.1101/486423
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