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Design and characterisation of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems
View ORCID ProfileRachel J. Harding, Peter Loppnau, View ORCID ProfileSuzanne Ackloo, Alexander Lemak, Ashley Hutchinson, Brittany Hunt, View ORCID ProfileAlex S. Holehouse, View ORCID ProfileJolene C. Ho, Lixin Fan, View ORCID ProfileLeticia Toledo-Sherman, Alma Seitova, View ORCID ProfileCheryl H. Arrowsmith
doi: https://doi.org/10.1101/492215
Rachel J. Harding
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Peter Loppnau
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Suzanne Ackloo
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Alexander Lemak
2Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
Ashley Hutchinson
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Brittany Hunt
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Alex S. Holehouse
3Department of Biomedical Engineering and Center for Biological Systems Engineering, Washington University in Saint Louis, Saint Louis, Missouri 63130, USA
Jolene C. Ho
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Lixin Fan
4Basic Science Program, SAXS Core facility of National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA
Leticia Toledo-Sherman
5CHDI Foundation, 6080 Center Drive, Suite 700, Los Angeles, CA 90045, USA
Alma Seitova
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
Cheryl H. Arrowsmith
1Structural Genomics Consortium, University of Toronto, MaRS South Tower, 101 College Street, Toronto, Ontario M5G 1L7, Canada
2Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada
Posted December 10, 2018.
Design and characterisation of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems
Rachel J. Harding, Peter Loppnau, Suzanne Ackloo, Alexander Lemak, Ashley Hutchinson, Brittany Hunt, Alex S. Holehouse, Jolene C. Ho, Lixin Fan, Leticia Toledo-Sherman, Alma Seitova, Cheryl H. Arrowsmith
bioRxiv 492215; doi: https://doi.org/10.1101/492215
Design and characterisation of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems
Rachel J. Harding, Peter Loppnau, Suzanne Ackloo, Alexander Lemak, Ashley Hutchinson, Brittany Hunt, Alex S. Holehouse, Jolene C. Ho, Lixin Fan, Leticia Toledo-Sherman, Alma Seitova, Cheryl H. Arrowsmith
bioRxiv 492215; doi: https://doi.org/10.1101/492215
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