New Results
Structural basis for activation of Dot1L methyltransferase on the nucleosome by histone H2BK120 ubiquitylation
Cathy J. Anderson, Matthew R. Baird, Allen Hsu, Emily H. Barbour, Yuka Koyama, Mario J. Borgnia, Robert K. McGinty
doi: https://doi.org/10.1101/503128
Cathy J. Anderson
1Department of Biochemistry and Biophysics, School of Medicine, The University of North Carolina, Chapel Hill, NC 27599, USA
Matthew R. Baird
2Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina, Chapel Hill, NC 27599, USA
4Present address: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Allen Hsu
3Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709
Emily H. Barbour
2Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina, Chapel Hill, NC 27599, USA
Yuka Koyama
2Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina, Chapel Hill, NC 27599, USA
Mario J. Borgnia
3Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709
Robert K. McGinty
2Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, The University of North Carolina, Chapel Hill, NC 27599, USA
Article usage
Posted December 20, 2018.
Structural basis for activation of Dot1L methyltransferase on the nucleosome by histone H2BK120 ubiquitylation
Cathy J. Anderson, Matthew R. Baird, Allen Hsu, Emily H. Barbour, Yuka Koyama, Mario J. Borgnia, Robert K. McGinty
bioRxiv 503128; doi: https://doi.org/10.1101/503128
Subject Area
Subject Areas
- Biochemistry (11718)
- Bioengineering (8724)
- Bioinformatics (29132)
- Biophysics (14936)
- Cancer Biology (12051)
- Cell Biology (17360)
- Clinical Trials (138)
- Developmental Biology (9406)
- Ecology (14146)
- Epidemiology (2067)
- Evolutionary Biology (18269)
- Genetics (12223)
- Genomics (16768)
- Immunology (11844)
- Microbiology (28016)
- Molecular Biology (11560)
- Neuroscience (60822)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3231)
- Physiology (4940)
- Plant Biology (10401)
- Synthetic Biology (2878)
- Systems Biology (7333)
- Zoology (1642)