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Measuring Granger-causal effects in multivariate time series by system editing

View ORCID ProfileRoberto D. Pascual-Marqui, Rolando J. Biscay, Jorge Bosch-Bayard, Pascal Faber, Toshihiko Kinoshita, Kieko Kochi, Patricia Milz, Keiichiro Nishida, Masafumi Yoshimura
doi: https://doi.org/10.1101/504068
Roberto D. Pascual-Marqui
1The KEY Institute for Brain-Mind Research, Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospital of Psychiatry, Zurich, Switzerland
2Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
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  • ORCID record for Roberto D. Pascual-Marqui
Rolando J. Biscay
3Centro de Investigacion en Matematicas, Guanajuato, Mexico
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Jorge Bosch-Bayard
4Departamento de Neurobiologia Conductual y Cognitiva, Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico
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Pascal Faber
1The KEY Institute for Brain-Mind Research, Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospital of Psychiatry, Zurich, Switzerland
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Toshihiko Kinoshita
2Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
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Kieko Kochi
1The KEY Institute for Brain-Mind Research, Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospital of Psychiatry, Zurich, Switzerland
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Patricia Milz
1The KEY Institute for Brain-Mind Research, Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospital of Psychiatry, Zurich, Switzerland
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Keiichiro Nishida
2Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
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Masafumi Yoshimura
2Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
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1. Abstract

What is the role of each node in a system of many interconnected nodes? This can be quantified by comparing the dynamics of the nodes in the intact system, with their modified dynamics in the edited system, where one node is deleted. In detail, the spectra are calculated from a causal multivariate autoregressive model for the intact system. Next, without re-estimation, one node is deleted from the model and the modified spectra at all other nodes are re-calculated. The change in spectra from the edited system to the intact system quantifies the role of the deleted node, giving a measure of its Granger-causal effects (CFX) on the system. A generalization of this novel measure is available for networks (i.e. for groups of nodes), which quantifies the role of each network in a system of many networks. For the sake of reproducible research, program codes (PASCAL), executable file, and toy data in human readable format are included in the supplementary material.

Footnotes

  • Supplementary material will be added, and this is now declared in the abstract and conclusions

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted December 30, 2018.
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Measuring Granger-causal effects in multivariate time series by system editing
Roberto D. Pascual-Marqui, Rolando J. Biscay, Jorge Bosch-Bayard, Pascal Faber, Toshihiko Kinoshita, Kieko Kochi, Patricia Milz, Keiichiro Nishida, Masafumi Yoshimura
bioRxiv 504068; doi: https://doi.org/10.1101/504068
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Measuring Granger-causal effects in multivariate time series by system editing
Roberto D. Pascual-Marqui, Rolando J. Biscay, Jorge Bosch-Bayard, Pascal Faber, Toshihiko Kinoshita, Kieko Kochi, Patricia Milz, Keiichiro Nishida, Masafumi Yoshimura
bioRxiv 504068; doi: https://doi.org/10.1101/504068

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