New Results
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
Robert Vander Velde, Nara Yoon, Viktoriya Marusyk, Arda Durmaz, Andrew Dhawan, Daria Myroshnychenko, Diego Lozano-Peral, Bina Desai, Olena Balynska, Jan Poleszhuk, Liu Kenian, Mohamed Abazeed, Omar Mian, Aik Choon Tan, Eric Haura, Jacob Scott, Andriy Marusyk
doi: https://doi.org/10.1101/504837
Robert Vander Velde
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
2Department of Molecular Medicine, University of South Florida, Tampa, FL, USA.
Nara Yoon
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
Viktoriya Marusyk
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Arda Durmaz
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
4Systems Biology and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Andrew Dhawan
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
Daria Myroshnychenko
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Diego Lozano-Peral
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
6University of Málaga, Málaga, Spain.
Bina Desai
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
5University of South Florida Cancer Biology PhD Program, Tampa, FL, USA.
Olena Balynska
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Jan Poleszhuk
7Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences.
Liu Kenian
8Department of Pathology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Mohamed Abazeed
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
Omar Mian
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
Aik Choon Tan
10Department of Biostatistic and Bioinformatics, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Eric Haura
9Department of Thoracic Oncology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Jacob Scott
3Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
4Systems Biology and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Andriy Marusyk
1Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
Posted November 19, 2019.
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
Robert Vander Velde, Nara Yoon, Viktoriya Marusyk, Arda Durmaz, Andrew Dhawan, Daria Myroshnychenko, Diego Lozano-Peral, Bina Desai, Olena Balynska, Jan Poleszhuk, Liu Kenian, Mohamed Abazeed, Omar Mian, Aik Choon Tan, Eric Haura, Jacob Scott, Andriy Marusyk
bioRxiv 504837; doi: https://doi.org/10.1101/504837
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
Robert Vander Velde, Nara Yoon, Viktoriya Marusyk, Arda Durmaz, Andrew Dhawan, Daria Myroshnychenko, Diego Lozano-Peral, Bina Desai, Olena Balynska, Jan Poleszhuk, Liu Kenian, Mohamed Abazeed, Omar Mian, Aik Choon Tan, Eric Haura, Jacob Scott, Andriy Marusyk
bioRxiv 504837; doi: https://doi.org/10.1101/504837
Subject Area
Subject Areas
- Biochemistry (11745)
- Bioengineering (8751)
- Bioinformatics (29195)
- Biophysics (14971)
- Cancer Biology (12095)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18306)
- Genetics (12245)
- Genomics (16801)
- Immunology (11867)
- Microbiology (28083)
- Molecular Biology (11592)
- Neuroscience (60965)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7339)
- Zoology (1651)