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A novel small molecule screening platform for disrupting toxic tau oligomers in cells

Chih Hung Lo, Colin Kin-Wye Lim, Zhipeng Ding, Sanjula Wickramasinghe, Anthony R. Braun, Elizabeth Rhoades, David D. Thomas, Jonathan N. Sachs
doi: https://doi.org/10.1101/510412
Chih Hung Lo
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
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Colin Kin-Wye Lim
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
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Zhipeng Ding
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
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Sanjula Wickramasinghe
2Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104
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Anthony R. Braun
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
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Elizabeth Rhoades
2Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104
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David D. Thomas
3Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455
4Photonic Pharma LLC, Minneapolis, MN 55410
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Jonathan N. Sachs
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
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  • For correspondence: jnsachs@umn.edu
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Article Information

doi 
https://doi.org/10.1101/510412
History 
  • January 3, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Chih Hung Lo1,
  2. Colin Kin-Wye Lim1,
  3. Zhipeng Ding1,
  4. Sanjula Wickramasinghe2,
  5. Anthony R. Braun1,
  6. Elizabeth Rhoades2,
  7. David D. Thomas3,4 and
  8. Jonathan N. Sachs1,*
  1. 1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
  2. 2Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104
  3. 3Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455
  4. 4Photonic Pharma LLC, Minneapolis, MN 55410
  1. ↵*To whom correspondence should be addressed: jnsachs{at}umn.edu
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Posted January 03, 2019.
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A novel small molecule screening platform for disrupting toxic tau oligomers in cells
Chih Hung Lo, Colin Kin-Wye Lim, Zhipeng Ding, Sanjula Wickramasinghe, Anthony R. Braun, Elizabeth Rhoades, David D. Thomas, Jonathan N. Sachs
bioRxiv 510412; doi: https://doi.org/10.1101/510412
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A novel small molecule screening platform for disrupting toxic tau oligomers in cells
Chih Hung Lo, Colin Kin-Wye Lim, Zhipeng Ding, Sanjula Wickramasinghe, Anthony R. Braun, Elizabeth Rhoades, David D. Thomas, Jonathan N. Sachs
bioRxiv 510412; doi: https://doi.org/10.1101/510412

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