Abstract
Megakaryocytes (MKs) are rare cells that develop in the bone marrow and give rise to platelets. A major challenge in studying megakaryocyte development, and the diseases that arise from these cells, is the identification and classification of MK progenitor cells that are produced during hematopoiesis. Here, we utilize combination image flow cytometry and principal component analysis (PCA) to definitively identify MK progenitor cell populations originating from a heterogeneous sample of bone marrow cells using minimal antibody panels.
Copyright
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Posted March 11, 2019.
Combination image flow cytometry reveals novel methods for isolating megakaryocyte progenitors cells
