New Results
NRF2-dependent metabolic reprogramming is required for tumor recurrence following oncogene inhibition
Douglas B. Fox, Ryan Lupo, Laura C. Noteware, Rachel Newcomb, Juan Liu, Jason W. Locasale, Matthew D. Hirschey, James V. Alvarez
doi: https://doi.org/10.1101/513994
Douglas B. Fox
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Ryan Lupo
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Laura C. Noteware
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Rachel Newcomb
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Juan Liu
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Jason W. Locasale
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Matthew D. Hirschey
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
2Department of Medicine, Division of Endocrinology, Metabolism, & Nutrition, Duke University Medical Center, Durham, NC 27710, USA
3Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Durham, NC 27701, USA
James V. Alvarez
1Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA
Posted January 08, 2019.
NRF2-dependent metabolic reprogramming is required for tumor recurrence following oncogene inhibition
Douglas B. Fox, Ryan Lupo, Laura C. Noteware, Rachel Newcomb, Juan Liu, Jason W. Locasale, Matthew D. Hirschey, James V. Alvarez
bioRxiv 513994; doi: https://doi.org/10.1101/513994
Subject Area
Subject Areas
- Biochemistry (11573)
- Bioengineering (8623)
- Bioinformatics (28875)
- Biophysics (14805)
- Cancer Biology (11944)
- Cell Biology (17170)
- Clinical Trials (138)
- Developmental Biology (9307)
- Ecology (14022)
- Epidemiology (2067)
- Evolutionary Biology (18129)
- Genetics (12148)
- Genomics (16619)
- Immunology (11712)
- Microbiology (27702)
- Molecular Biology (11401)
- Neuroscience (60106)
- Paleontology (448)
- Pathology (1849)
- Pharmacology and Toxicology (3184)
- Physiology (4878)
- Plant Biology (10279)
- Synthetic Biology (2849)
- Systems Biology (7291)
- Zoology (1619)