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Dynamic Change of Electrostatic Field in TMEM16F Permeation Pathway Shifts Its Ion Selectivity

View ORCID ProfileWenlei Ye, Tina W. Han, Mu He, Yuh Nung Jan, Lily Y. Jan
doi: https://doi.org/10.1101/515569
Wenlei Ye
1Department of Physiology, University of California, San Francisco, CA 94143
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  • ORCID record for Wenlei Ye
Tina W. Han
1Department of Physiology, University of California, San Francisco, CA 94143
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Mu He
1Department of Physiology, University of California, San Francisco, CA 94143
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Yuh Nung Jan
1Department of Physiology, University of California, San Francisco, CA 94143
2Department of Physiology, Howard Hughes Medical Institute, University of California, San Francisco, CA 94143
3Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143
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Lily Y. Jan
1Department of Physiology, University of California, San Francisco, CA 94143
2Department of Physiology, Howard Hughes Medical Institute, University of California, San Francisco, CA 94143
3Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143
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  • For correspondence: Lily.Jan@ucsf.edu
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Article Information

doi 
https://doi.org/10.1101/515569
History 
  • January 16, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Wenlei Ye1,
  2. Tina W. Han1,
  3. Mu He1,
  4. Yuh Nung Jan1,2,3 and
  5. Lily Y. Jan1,2,3,*
  1. 1Department of Physiology, University of California, San Francisco, CA 94143
  2. 2Department of Physiology, Howard Hughes Medical Institute, University of California, San Francisco, CA 94143
  3. 3Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143
  1. ↵*To whom correspondence should be addressed. Email: Lily.Jan{at}ucsf.edu.
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Posted January 16, 2019.
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Dynamic Change of Electrostatic Field in TMEM16F Permeation Pathway Shifts Its Ion Selectivity
Wenlei Ye, Tina W. Han, Mu He, Yuh Nung Jan, Lily Y. Jan
bioRxiv 515569; doi: https://doi.org/10.1101/515569
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Dynamic Change of Electrostatic Field in TMEM16F Permeation Pathway Shifts Its Ion Selectivity
Wenlei Ye, Tina W. Han, Mu He, Yuh Nung Jan, Lily Y. Jan
bioRxiv 515569; doi: https://doi.org/10.1101/515569

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