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A sustained small increase in NOD1 expression promotes ligand-independent oncogenic activity

Leah M. Rommereim, Ajay Suresh Akhade, Bhaskar Dutta, Carolyn Hutcheon, Nicolas W. Lounsbury, Clifford C. Rostomily, Ram Savan, Iain D. C. Fraser, Ronald N. Germain, Naeha Subramanian
doi: https://doi.org/10.1101/518886
Leah M. Rommereim
1Institute for Systems Biology, Seattle, WA, 98109, USA.
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Ajay Suresh Akhade
1Institute for Systems Biology, Seattle, WA, 98109, USA.
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Bhaskar Dutta
2Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892-0421, USA.
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Carolyn Hutcheon
1Institute for Systems Biology, Seattle, WA, 98109, USA.
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Nicolas W. Lounsbury
2Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892-0421, USA.
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Clifford C. Rostomily
1Institute for Systems Biology, Seattle, WA, 98109, USA.
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Ram Savan
3Department of Immunology, University of Washington, Seattle, WA, 98109, USA.
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Iain D. C. Fraser
2Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892-0421, USA.
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Ronald N. Germain
2Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892-0421, USA.
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Naeha Subramanian
1Institute for Systems Biology, Seattle, WA, 98109, USA.
3Department of Immunology, University of Washington, Seattle, WA, 98109, USA.
4Department of Global Health, University of Washington, Seattle, WA, 98109, USA.
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  • For correspondence: nsubrama@systemsbiology.org
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Article Information

doi 
https://doi.org/10.1101/518886
History 
  • January 21, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Leah M. Rommereim1,†,
  2. Ajay Suresh Akhade1,†,
  3. Bhaskar Dutta2,†,
  4. Carolyn Hutcheon1,
  5. Nicolas W. Lounsbury2,
  6. Clifford C. Rostomily1,
  7. Ram Savan3,
  8. Iain D. C. Fraser2,
  9. Ronald N. Germain2 and
  10. Naeha Subramanian1,3,4,*
  1. 1Institute for Systems Biology, Seattle, WA, 98109, USA.
  2. 2Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892-0421, USA.
  3. 3Department of Immunology, University of Washington, Seattle, WA, 98109, USA.
  4. 4Department of Global Health, University of Washington, Seattle, WA, 98109, USA.
  1. ↵*Correspondence to: nsubrama{at}systemsbiology.org
  1. ↵† Equal contributions

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Posted January 21, 2019.
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A sustained small increase in NOD1 expression promotes ligand-independent oncogenic activity
Leah M. Rommereim, Ajay Suresh Akhade, Bhaskar Dutta, Carolyn Hutcheon, Nicolas W. Lounsbury, Clifford C. Rostomily, Ram Savan, Iain D. C. Fraser, Ronald N. Germain, Naeha Subramanian
bioRxiv 518886; doi: https://doi.org/10.1101/518886
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A sustained small increase in NOD1 expression promotes ligand-independent oncogenic activity
Leah M. Rommereim, Ajay Suresh Akhade, Bhaskar Dutta, Carolyn Hutcheon, Nicolas W. Lounsbury, Clifford C. Rostomily, Ram Savan, Iain D. C. Fraser, Ronald N. Germain, Naeha Subramanian
bioRxiv 518886; doi: https://doi.org/10.1101/518886

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