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Highly-accurate long-read sequencing improves variant detection and assembly of a human genome
View ORCID ProfileAaron M. Wenger, Paul Peluso, William J. Rowell, Pi-Chuan Chang, Richard J. Hall, Gregory T. Concepcion, Jana Ebler, Arkarachai Fungtammasan, Alexey Kolesnikov, Nathan D. Olson, Armin Töpfer, Chen-Shan Chin, Michael Alonge, Medhat Mahmoud, Yufeng Qian, Adam M. Phillippy, Michael C. Schatz, Gene Myers, Mark A. DePristo, Jue Ruan, Tobias Marschall, Fritz J. Sedlazeck, Justin M. Zook, Heng Li, Sergey Koren, Andrew Carroll, David R. Rank, Michael W. Hunkapiller
doi: https://doi.org/10.1101/519025
Aaron M. Wenger
1Pacific Biosciences, Menlo Park, CA, USA
Paul Peluso
1Pacific Biosciences, Menlo Park, CA, USA
William J. Rowell
1Pacific Biosciences, Menlo Park, CA, USA
Pi-Chuan Chang
2Google Inc., Mountain View, CA, USA
Richard J. Hall
1Pacific Biosciences, Menlo Park, CA, USA
Gregory T. Concepcion
1Pacific Biosciences, Menlo Park, CA, USA
Jana Ebler
3Center for Bioinformatics, Saarland University, Saarbrücken, Germany
4Max Planck Institute for Informatics, Saarland Informatics Campus E1.4, Saarbrücken, Germany
5Graduate School of Computer Science, Saarland University, Saarland Informatics Campus E1.3, Saarbrücken, Germany
Arkarachai Fungtammasan
6DNAnexus, Mountain View, CA, USA
Alexey Kolesnikov
2Google Inc., Mountain View, CA, USA
Nathan D. Olson
7National Institute of Standards and Technology, Gaithersburg, MD, USA
Armin Töpfer
1Pacific Biosciences, Menlo Park, CA, USA
Chen-Shan Chin
6DNAnexus, Mountain View, CA, USA
Michael Alonge
8Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA
Medhat Mahmoud
9Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
Yufeng Qian
1Pacific Biosciences, Menlo Park, CA, USA
Adam M. Phillippy
10Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA
Michael C. Schatz
8Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA
Gene Myers
11Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Mark A. DePristo
2Google Inc., Mountain View, CA, USA
Jue Ruan
12Agricultural Genomics Institute, Chinese Academy of Agriculture Sciences, Shenzen, China
Tobias Marschall
3Center for Bioinformatics, Saarland University, Saarbrücken, Germany
4Max Planck Institute for Informatics, Saarland Informatics Campus E1.4, Saarbrücken, Germany
Fritz J. Sedlazeck
9Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
Justin M. Zook
7National Institute of Standards and Technology, Gaithersburg, MD, USA
Heng Li
13Dana-Farber Cancer Institute, Boston, MA, USA
Sergey Koren
10Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA
Andrew Carroll
2Google Inc., Mountain View, CA, USA
David R. Rank
1Pacific Biosciences, Menlo Park, CA, USA
Michael W. Hunkapiller
1Pacific Biosciences, Menlo Park, CA, USA
Posted January 13, 2019.
Highly-accurate long-read sequencing improves variant detection and assembly of a human genome
Aaron M. Wenger, Paul Peluso, William J. Rowell, Pi-Chuan Chang, Richard J. Hall, Gregory T. Concepcion, Jana Ebler, Arkarachai Fungtammasan, Alexey Kolesnikov, Nathan D. Olson, Armin Töpfer, Chen-Shan Chin, Michael Alonge, Medhat Mahmoud, Yufeng Qian, Adam M. Phillippy, Michael C. Schatz, Gene Myers, Mark A. DePristo, Jue Ruan, Tobias Marschall, Fritz J. Sedlazeck, Justin M. Zook, Heng Li, Sergey Koren, Andrew Carroll, David R. Rank, Michael W. Hunkapiller
bioRxiv 519025; doi: https://doi.org/10.1101/519025
Highly-accurate long-read sequencing improves variant detection and assembly of a human genome
Aaron M. Wenger, Paul Peluso, William J. Rowell, Pi-Chuan Chang, Richard J. Hall, Gregory T. Concepcion, Jana Ebler, Arkarachai Fungtammasan, Alexey Kolesnikov, Nathan D. Olson, Armin Töpfer, Chen-Shan Chin, Michael Alonge, Medhat Mahmoud, Yufeng Qian, Adam M. Phillippy, Michael C. Schatz, Gene Myers, Mark A. DePristo, Jue Ruan, Tobias Marschall, Fritz J. Sedlazeck, Justin M. Zook, Heng Li, Sergey Koren, Andrew Carroll, David R. Rank, Michael W. Hunkapiller
bioRxiv 519025; doi: https://doi.org/10.1101/519025
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