Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals

Shu Tadaka, Fumiki Katsuoka, Masao Ueki, Kaname Kojima, Satoshi Makino, Sakae Saito, Akihito Otsuki, Chinatsu Gocho, Mika Sakurai-Yageta, Inaho Danjo, Ikuko N. Motoike, Yumi Yamaguchi-Kabata, Matsuyuki Shirota, Seizo Koshiba, Masao Nagasaki, Naoko Minegishi, Atsushi Hozawa, Shinichi Kuriyama, Atsushi Shimizu, Jun Yasuda, Nobuo Fuse, The Tohoku Medical Megabank Project Study Group, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita
doi: https://doi.org/10.1101/529529
Shu Tadaka
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fumiki Katsuoka
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Masao Ueki
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kaname Kojima
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Satoshi Makino
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sakae Saito
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Akihito Otsuki
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chinatsu Gocho
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mika Sakurai-Yageta
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Inaho Danjo
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ikuko N. Motoike
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yumi Yamaguchi-Kabata
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matsuyuki Shirota
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Seizo Koshiba
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Masao Nagasaki
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Naoko Minegishi
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Atsushi Hozawa
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shinichi Kuriyama
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Atsushi Shimizu
Iwate Tohoku Medical Megabank Organization, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jun Yasuda
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nobuo Fuse
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
-
Gen Tamiya
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Masayuki Yamamoto
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kengo Kinoshita
Tohoku Medical Megabank Organization, Tohoku University, Japan;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: kengo@ecei.tohoku.ac.jp
  • Abstract
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

The first step towards realizing personalized healthcare is to catalog the genetic variations in a population. Since the dissemination of individual-level genomic information is strictly controlled, it will be useful to construct population-level allele frequency panels and to provide them through easy-to-use interfaces. In the Tohoku Medical Megabank Project, we have sequenced nearly 4,000 individuals from a Japanese population, and constructed an allele frequency panel of 3,552 individuals after removing related samples. The panel is called the 3.5KJPNv2. It was constructed by using a standard pipeline including the 1KGP and gnomAD algorithms to reduce technical biases and to allow comparisons to other populations. Our database is the first largescale panel providing the frequencies of variants present oN the X chromosome and on the mitochondria in the Japanese https://jmorp.megabank.tohoku.ac.jp.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.
Back to top
PreviousNext
Posted January 25, 2019.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
Share
3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals
Shu Tadaka, Fumiki Katsuoka, Masao Ueki, Kaname Kojima, Satoshi Makino, Sakae Saito, Akihito Otsuki, Chinatsu Gocho, Mika Sakurai-Yageta, Inaho Danjo, Ikuko N. Motoike, Yumi Yamaguchi-Kabata, Matsuyuki Shirota, Seizo Koshiba, Masao Nagasaki, Naoko Minegishi, Atsushi Hozawa, Shinichi Kuriyama, Atsushi Shimizu, Jun Yasuda, Nobuo Fuse, The Tohoku Medical Megabank Project Study Group, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita
bioRxiv 529529; doi: https://doi.org/10.1101/529529
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals
Shu Tadaka, Fumiki Katsuoka, Masao Ueki, Kaname Kojima, Satoshi Makino, Sakae Saito, Akihito Otsuki, Chinatsu Gocho, Mika Sakurai-Yageta, Inaho Danjo, Ikuko N. Motoike, Yumi Yamaguchi-Kabata, Matsuyuki Shirota, Seizo Koshiba, Masao Nagasaki, Naoko Minegishi, Atsushi Hozawa, Shinichi Kuriyama, Atsushi Shimizu, Jun Yasuda, Nobuo Fuse, The Tohoku Medical Megabank Project Study Group, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita
bioRxiv 529529; doi: https://doi.org/10.1101/529529

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (1544)
  • Biochemistry (2500)
  • Bioengineering (1757)
  • Bioinformatics (9727)
  • Biophysics (3928)
  • Cancer Biology (2990)
  • Cell Biology (4235)
  • Clinical Trials (135)
  • Developmental Biology (2653)
  • Ecology (4129)
  • Epidemiology (2033)
  • Evolutionary Biology (6931)
  • Genetics (5243)
  • Genomics (6531)
  • Immunology (2206)
  • Microbiology (7012)
  • Molecular Biology (2781)
  • Neuroscience (17410)
  • Paleontology (127)
  • Pathology (432)
  • Pharmacology and Toxicology (712)
  • Physiology (1068)
  • Plant Biology (2515)
  • Scientific Communication and Education (647)
  • Synthetic Biology (835)
  • Systems Biology (2698)
  • Zoology (439)