New Results
Huntington’s disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms
Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, Jong-Min Lee, Kevin Correia, Jacob Loupe, Kyung-Hee Kim, Douglas Barker, Eun Pyo Hong, Michael J Chao, Jeffrey D. Long, Diane Lucente, Jean-Paul Vonsattel, Ricardo Mouro Pinto, Kawther Abu Elneel, Eliana Marisa Ramos, Jayalakshmi Srinidhi Mysore, Tammy Gillis, Vanessa C. Wheeler, Marcy E. MacDonald, James F Gusella, Thomas Massey, Branduff McAllister, Christopher Medway, Timothy C Stone, Lynsey Hall, Lesley Jones, Peter Holmans, Seung Kwak, Anka Ehrhardt, Cristina Sampaio, Marc Ciosi, Alastair Maxwell, Afroditi Chatzi, Darren G Monckton, Michael Orth, G. Bernhard Landwehrmeyer, Jane S Paulsen, E. Ray Dorsey, Ira Shoulson, Richard H Myers
doi: https://doi.org/10.1101/529768
2Massachusetts General Hospital/Harvard Medical School;
Jong-Min Lee
2Massachusetts General Hospital/Harvard Medical School;
Kevin Correia
3Massachusetts General Hospital;
Jacob Loupe
3Massachusetts General Hospital;
Kyung-Hee Kim
3Massachusetts General Hospital;
Douglas Barker
3Massachusetts General Hospital;
Eun Pyo Hong
3Massachusetts General Hospital;
Michael J Chao
3Massachusetts General Hospital;
Jeffrey D. Long
4University of Iowa;
Diane Lucente
3Massachusetts General Hospital;
Jean-Paul Vonsattel
5Columbia University;
Ricardo Mouro Pinto
2Massachusetts General Hospital/Harvard Medical School;
Kawther Abu Elneel
3Massachusetts General Hospital;
Eliana Marisa Ramos
3Massachusetts General Hospital;
Jayalakshmi Srinidhi Mysore
3Massachusetts General Hospital;
Tammy Gillis
3Massachusetts General Hospital;
Vanessa C. Wheeler
2Massachusetts General Hospital/Harvard Medical School;
Marcy E. MacDonald
2Massachusetts General Hospital/Harvard Medical School;
James F Gusella
2Massachusetts General Hospital/Harvard Medical School;
Thomas Massey
6Cardiff University;
Branduff McAllister
6Cardiff University;
Christopher Medway
6Cardiff University;
Timothy C Stone
6Cardiff University;
Lynsey Hall
6Cardiff University;
Lesley Jones
6Cardiff University;
Peter Holmans
6Cardiff University;
Seung Kwak
7CHDI Foundation Inc.;
Anka Ehrhardt
7CHDI Foundation Inc.;
Cristina Sampaio
7CHDI Foundation Inc.;
Marc Ciosi
8University of Glasgow;
Alastair Maxwell
8University of Glasgow;
Afroditi Chatzi
8University of Glasgow;
Darren G Monckton
8University of Glasgow;
Michael Orth
9University of Ulm;
G. Bernhard Landwehrmeyer
9University of Ulm;
Jane S Paulsen
4University of Iowa;
E. Ray Dorsey
10University of Rochester;
Ira Shoulson
10University of Rochester;
Richard H Myers
11Boston University
Article usage
Posted January 24, 2019.
Huntington’s disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms
Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, Jong-Min Lee, Kevin Correia, Jacob Loupe, Kyung-Hee Kim, Douglas Barker, Eun Pyo Hong, Michael J Chao, Jeffrey D. Long, Diane Lucente, Jean-Paul Vonsattel, Ricardo Mouro Pinto, Kawther Abu Elneel, Eliana Marisa Ramos, Jayalakshmi Srinidhi Mysore, Tammy Gillis, Vanessa C. Wheeler, Marcy E. MacDonald, James F Gusella, Thomas Massey, Branduff McAllister, Christopher Medway, Timothy C Stone, Lynsey Hall, Lesley Jones, Peter Holmans, Seung Kwak, Anka Ehrhardt, Cristina Sampaio, Marc Ciosi, Alastair Maxwell, Afroditi Chatzi, Darren G Monckton, Michael Orth, G. Bernhard Landwehrmeyer, Jane S Paulsen, E. Ray Dorsey, Ira Shoulson, Richard H Myers
bioRxiv 529768; doi: https://doi.org/10.1101/529768
Huntington’s disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms
Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, Jong-Min Lee, Kevin Correia, Jacob Loupe, Kyung-Hee Kim, Douglas Barker, Eun Pyo Hong, Michael J Chao, Jeffrey D. Long, Diane Lucente, Jean-Paul Vonsattel, Ricardo Mouro Pinto, Kawther Abu Elneel, Eliana Marisa Ramos, Jayalakshmi Srinidhi Mysore, Tammy Gillis, Vanessa C. Wheeler, Marcy E. MacDonald, James F Gusella, Thomas Massey, Branduff McAllister, Christopher Medway, Timothy C Stone, Lynsey Hall, Lesley Jones, Peter Holmans, Seung Kwak, Anka Ehrhardt, Cristina Sampaio, Marc Ciosi, Alastair Maxwell, Afroditi Chatzi, Darren G Monckton, Michael Orth, G. Bernhard Landwehrmeyer, Jane S Paulsen, E. Ray Dorsey, Ira Shoulson, Richard H Myers
bioRxiv 529768; doi: https://doi.org/10.1101/529768
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