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Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis

Wei Li, Jing Hu, Bi Shi, Francesco Palomba, Michelle A. Digman, Enrico Gratton, Hao Jiang
doi: https://doi.org/10.1101/536839
Wei Li
1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
2Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
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Jing Hu
1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
2Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
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Bi Shi
1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
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Francesco Palomba
3Laboratory of Fluorescence Dynamics, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA
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Michelle A. Digman
3Laboratory of Fluorescence Dynamics, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA
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Enrico Gratton
3Laboratory of Fluorescence Dynamics, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA
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Hao Jiang
1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
2Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
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  • For correspondence: hj8d@virginia.edu
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Article Information

doi 
https://doi.org/10.1101/536839
History 
  • June 9, 2020.

Article Versions

  • Version 1 (January 31, 2019 - 14:27).
  • Version 2 (February 18, 2019 - 16:09).
  • You are viewing Version 3, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Wei Li1,2,*,
  2. Jing Hu1,2,*,
  3. Bi Shi1,*,
  4. Francesco Palomba3,
  5. Michelle A. Digman3,
  6. Enrico Gratton3 and
  7. Hao Jiang1,2,#
  1. 1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
  2. 2Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA
  3. 3Laboratory of Fluorescence Dynamics, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA
  1. ↵#Correspondence should be addressed to H.J. Corresponding author
    Correspondence should be addressed to Hao Jiang (hj8d{at}virginia.edu).
  1. ↵* These authors contributed equally to this work.

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Posted June 09, 2020.
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Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
Wei Li, Jing Hu, Bi Shi, Francesco Palomba, Michelle A. Digman, Enrico Gratton, Hao Jiang
bioRxiv 536839; doi: https://doi.org/10.1101/536839
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Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
Wei Li, Jing Hu, Bi Shi, Francesco Palomba, Michelle A. Digman, Enrico Gratton, Hao Jiang
bioRxiv 536839; doi: https://doi.org/10.1101/536839

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