New Results
Tissue structure accelerates evolution: premalignant sweeps precede neutral expansion
View ORCID ProfileJeffrey West, View ORCID ProfileRyan O. Schenck, View ORCID ProfileChandler Gatenbee, View ORCID ProfileMark Robertson-Tessi, View ORCID ProfileAlexander R. A. Anderson
doi: https://doi.org/10.1101/542019
Jeffrey West
1Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4 Rm 24000H Tampa, Florida, 33612
Ryan O. Schenck
1Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4 Rm 24000H Tampa, Florida, 33612
2Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX37BN, UK
Chandler Gatenbee
1Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4 Rm 24000H Tampa, Florida, 33612
Mark Robertson-Tessi
1Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4 Rm 24000H Tampa, Florida, 33612
Alexander R. A. Anderson
1Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, SRB 4 Rm 24000H Tampa, Florida, 33612
Posted February 10, 2019.
Tissue structure accelerates evolution: premalignant sweeps precede neutral expansion
Jeffrey West, Ryan O. Schenck, Chandler Gatenbee, Mark Robertson-Tessi, Alexander R. A. Anderson
bioRxiv 542019; doi: https://doi.org/10.1101/542019
Subject Area
Subject Areas
- Biochemistry (11573)
- Bioengineering (8623)
- Bioinformatics (28875)
- Biophysics (14805)
- Cancer Biology (11944)
- Cell Biology (17170)
- Clinical Trials (138)
- Developmental Biology (9307)
- Ecology (14022)
- Epidemiology (2067)
- Evolutionary Biology (18129)
- Genetics (12148)
- Genomics (16619)
- Immunology (11712)
- Microbiology (27702)
- Molecular Biology (11401)
- Neuroscience (60106)
- Paleontology (448)
- Pathology (1849)
- Pharmacology and Toxicology (3184)
- Physiology (4878)
- Plant Biology (10279)
- Synthetic Biology (2849)
- Systems Biology (7291)
- Zoology (1619)