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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

Farnaz Fekri, John Abousawan, Stephen Bautista, Roya M. Dayam, Costin N. Antonescu, Raffi Karshafian
doi: https://doi.org/10.1101/543355
Farnaz Fekri
1Department of Chemistry and Biology Ryerson University, Toronto Ontario, Canada, M5B 2K3
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
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John Abousawan
1Department of Chemistry and Biology Ryerson University, Toronto Ontario, Canada, M5B 2K3
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
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Stephen Bautista
1Department of Chemistry and Biology Ryerson University, Toronto Ontario, Canada, M5B 2K3
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
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Roya M. Dayam
1Department of Chemistry and Biology Ryerson University, Toronto Ontario, Canada, M5B 2K3
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
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Costin N. Antonescu
1Department of Chemistry and Biology Ryerson University, Toronto Ontario, Canada, M5B 2K3
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
5Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, Toronto, Ontario, Canada
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  • For correspondence: cantonescu@ryerson.ca karshafian@ryerson.ca
Raffi Karshafian
2Graduate Program in Molecular Science, Toronto Ontario, Canada, M5B 2K3
3Department of Physics, Ryerson University, Toronto Ontario, Canada, M5B 2K3
4Institute for Biomedical Engineering, Science and Technology (iBEST), a partnership between Ryerson University and St. Michael’s Hospital, Toronto, Ontario, Canada
5Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, Toronto, Ontario, Canada
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  • For correspondence: cantonescu@ryerson.ca karshafian@ryerson.ca
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Posted February 07, 2019.
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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs
Farnaz Fekri, John Abousawan, Stephen Bautista, Roya M. Dayam, Costin N. Antonescu, Raffi Karshafian
bioRxiv 543355; doi: https://doi.org/10.1101/543355
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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs
Farnaz Fekri, John Abousawan, Stephen Bautista, Roya M. Dayam, Costin N. Antonescu, Raffi Karshafian
bioRxiv 543355; doi: https://doi.org/10.1101/543355

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