New Results
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis
View ORCID ProfilePaula MacGregor, Andrea L. Gonzalez-Munoz, Fatoumatta Jobe, View ORCID ProfileMartin C. Taylor, Steven Rust, Alan M. Sandercock, Olivia J.S. Macleod, View ORCID ProfileKatrien Van Bocxlaer, Amanda F. Francisco, Francois D’Hooge, View ORCID ProfileArnaud Tiberghien, Conor S. Barry, View ORCID ProfilePhilip Howard, View ORCID ProfileMatthew K. Higgins, Tristan J. Vaughan, View ORCID ProfileRalph Minter, View ORCID ProfileMark Carrington
doi: https://doi.org/10.1101/547208
Paula MacGregor
aDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW
Andrea L. Gonzalez-Munoz
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Fatoumatta Jobe
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Martin C. Taylor
cLondon School of Hygiene and Tropical Medicine, London, WC1E 7HT
Steven Rust
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Alan M. Sandercock
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Olivia J.S. Macleod
aDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW
Katrien Van Bocxlaer
cLondon School of Hygiene and Tropical Medicine, London, WC1E 7HT
Amanda F. Francisco
cLondon School of Hygiene and Tropical Medicine, London, WC1E 7HT
Francois D’Hooge
dSpirogen Ltd, The QMB Innovation Centre, New Road, London, E1 2AX
Arnaud Tiberghien
dSpirogen Ltd, The QMB Innovation Centre, New Road, London, E1 2AX
Conor S. Barry
dSpirogen Ltd, The QMB Innovation Centre, New Road, London, E1 2AX
Philip Howard
dSpirogen Ltd, The QMB Innovation Centre, New Road, London, E1 2AX
Matthew K. Higgins
eDepartment of Biochemistry, South Parks Road, University of Oxford, OX1 3QU
Tristan J. Vaughan
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Ralph Minter
bDepartment of Antibody Discovery and Protein Engineering, Medimmune, Granta Park, Cambridge, CB21 6GH
Mark Carrington
aDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW
Article usage
Posted February 11, 2019.
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis
Paula MacGregor, Andrea L. Gonzalez-Munoz, Fatoumatta Jobe, Martin C. Taylor, Steven Rust, Alan M. Sandercock, Olivia J.S. Macleod, Katrien Van Bocxlaer, Amanda F. Francisco, Francois D’Hooge, Arnaud Tiberghien, Conor S. Barry, Philip Howard, Matthew K. Higgins, Tristan J. Vaughan, Ralph Minter, Mark Carrington
bioRxiv 547208; doi: https://doi.org/10.1101/547208
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis
Paula MacGregor, Andrea L. Gonzalez-Munoz, Fatoumatta Jobe, Martin C. Taylor, Steven Rust, Alan M. Sandercock, Olivia J.S. Macleod, Katrien Van Bocxlaer, Amanda F. Francisco, Francois D’Hooge, Arnaud Tiberghien, Conor S. Barry, Philip Howard, Matthew K. Higgins, Tristan J. Vaughan, Ralph Minter, Mark Carrington
bioRxiv 547208; doi: https://doi.org/10.1101/547208
Subject Area
Subject Areas
- Biochemistry (11745)
- Bioengineering (8751)
- Bioinformatics (29195)
- Biophysics (14971)
- Cancer Biology (12095)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18306)
- Genetics (12245)
- Genomics (16801)
- Immunology (11867)
- Microbiology (28083)
- Molecular Biology (11592)
- Neuroscience (60965)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7339)
- Zoology (1651)