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Segmentation-Enhanced CycleGAN

View ORCID ProfileMichał Januszewski, View ORCID ProfileViren Jain
doi: https://doi.org/10.1101/548081
Michał Januszewski
1Google AI, Zürich, Switzerland
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Viren Jain
2Google AI, Mountain View, CA, USA
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Abstract

Algorithmic reconstruction of neurons from volume electron microscopy data traditionally requires training machine learning models on dataset-specific ground truth annotations that are expensive and tedious to acquire. We enhanced the training procedure of an unsupervised image-to-image translation method with additional components derived from an automated neuron segmentation approach. We show that this method, Segmentation-Enhanced CycleGAN (SECGAN), enables near perfect reconstruction accuracy on a benchmark connectomics segmentation dataset despite operating in a “zero-shot” setting in which the segmentation model was trained using only volumetric labels from a different dataset and imaging method. By reducing or eliminating the need for novel ground truth annotations, SECGANs alleviate one of the main practical burdens involved in pursuing automated reconstruction of volume electron microscopy data.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted February 13, 2019.
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Segmentation-Enhanced CycleGAN
Michał Januszewski, Viren Jain
bioRxiv 548081; doi: https://doi.org/10.1101/548081
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Segmentation-Enhanced CycleGAN
Michał Januszewski, Viren Jain
bioRxiv 548081; doi: https://doi.org/10.1101/548081

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