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Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

Charles A. Berdan, Raymond Ho, Haley S. Lehtola, Milton To, Xirui Hu, Tucker R. Huffman, Yana Petri, Chad R. Altobelli, Sasha G. Demeulenaere, James A. Olzmann, Thomas J. Maimone, View ORCID ProfileDaniel K. Nomura
doi: https://doi.org/10.1101/550806
Charles A. Berdan
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
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Raymond Ho
3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
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Haley S. Lehtola
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
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Milton To
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
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Xirui Hu
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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Tucker R. Huffman
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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Yana Petri
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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Chad R. Altobelli
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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Sasha G. Demeulenaere
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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James A. Olzmann
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
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Thomas J. Maimone
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
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  • For correspondence: maimone@berkeley.edu dnomura@berkeley.edu
Daniel K. Nomura
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
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  • ORCID record for Daniel K. Nomura
  • For correspondence: maimone@berkeley.edu dnomura@berkeley.edu
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Article Information

doi 
https://doi.org/10.1101/550806
History 
  • February 14, 2019.

Article Versions

  • Version 1 (February 14, 2019 - 16:51).
  • You are currently viewing Version 2 of this article (February 14, 2019 - 22:06).
  • View Version 3, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Charles A. Berdan1,
  2. Raymond Ho3,
  3. Haley S. Lehtola1,
  4. Milton To1,
  5. Xirui Hu2,
  6. Tucker R. Huffman2,
  7. Yana Petri2,
  8. Chad R. Altobelli2,
  9. Sasha G. Demeulenaere2,
  10. James A. Olzmann1,
  11. Thomas J. Maimone2,* and
  12. Daniel K. Nomura1,2,3,*
  1. 1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
  2. 2Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
  3. 3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
  1. ↵*correspondence to maimone{at}berkeley.edu and dnomura{at}berkeley.edu
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Posted February 14, 2019.
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Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells
Charles A. Berdan, Raymond Ho, Haley S. Lehtola, Milton To, Xirui Hu, Tucker R. Huffman, Yana Petri, Chad R. Altobelli, Sasha G. Demeulenaere, James A. Olzmann, Thomas J. Maimone, Daniel K. Nomura
bioRxiv 550806; doi: https://doi.org/10.1101/550806
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Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells
Charles A. Berdan, Raymond Ho, Haley S. Lehtola, Milton To, Xirui Hu, Tucker R. Huffman, Yana Petri, Chad R. Altobelli, Sasha G. Demeulenaere, James A. Olzmann, Thomas J. Maimone, Daniel K. Nomura
bioRxiv 550806; doi: https://doi.org/10.1101/550806

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