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Combinatorial mutagenesis of rapidly-evolving residues yields super-restrictor antiviral proteins
Rossana Colón-Thillet, Emily Hsieh, Laura Graf, View ORCID ProfileRichard N McLaughlin Jr, Janet M. Young, View ORCID ProfileGeorg Kochs, View ORCID ProfileMichael Emerman, View ORCID ProfileHarmit S. Malik
doi: https://doi.org/10.1101/557264
Rossana Colón-Thillet
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
4Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA
Emily Hsieh
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
2Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
4Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA
Laura Graf
6Institute of Virology, Medical Center-University of Freiburg
Richard N McLaughlin Jr
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
5Pacific Northwest Research Institute, Seattle, Washington, USA
Janet M. Young
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Georg Kochs
6Institute of Virology, Medical Center-University of Freiburg
7Faculty of Medicine, University of Freiburg, Freiburg, Germany
Michael Emerman
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
2Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Harmit S. Malik
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
3Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Posted August 12, 2019.
Combinatorial mutagenesis of rapidly-evolving residues yields super-restrictor antiviral proteins
Rossana Colón-Thillet, Emily Hsieh, Laura Graf, Richard N McLaughlin Jr, Janet M. Young, Georg Kochs, Michael Emerman, Harmit S. Malik
bioRxiv 557264; doi: https://doi.org/10.1101/557264
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