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Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination: A novel mechanism for enzymatic DNA synthesis
View ORCID ProfileK. Hoff, M. Halpain, G. Garbagnati, J. Edwards, W. Zhou
doi: https://doi.org/10.1101/561092
K. Hoff
1Department of Advanced Research and Development, Centrillion Biosciences, 2500 Faber Place, Palo Alto, CA 94303, USA
M. Halpain
1Department of Advanced Research and Development, Centrillion Biosciences, 2500 Faber Place, Palo Alto, CA 94303, USA
G. Garbagnati
1Department of Advanced Research and Development, Centrillion Biosciences, 2500 Faber Place, Palo Alto, CA 94303, USA
J. Edwards
1Department of Advanced Research and Development, Centrillion Biosciences, 2500 Faber Place, Palo Alto, CA 94303, USA
2Chemistry and Chemical Biology, University of New Mexico, Albuquerque, NM 87131, USA
3Internal Medicine, Chemical and Biological Engineering, University of New Mexico, Albuquerque, NM 87131, USA
4University of New Mexico Comprehensive Cancer Center, Albuquerque, NM 87131, USA
5University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
W. Zhou
1Department of Advanced Research and Development, Centrillion Biosciences, 2500 Faber Place, Palo Alto, CA 94303, USA
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Posted April 15, 2019.
Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination: A novel mechanism for enzymatic DNA synthesis
K. Hoff, M. Halpain, G. Garbagnati, J. Edwards, W. Zhou
bioRxiv 561092; doi: https://doi.org/10.1101/561092
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