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Cognitive capacity limits are remediated by practice-induced plasticity in a striatal-cortical network

View ORCID ProfileK.G. Garner, View ORCID ProfileM.I. Garrido, View ORCID ProfileP.E. Dux
doi: https://doi.org/10.1101/564450
K.G. Garner
1Queensland Brain Institute, University of Queensland, Brisbane, Australia
2School of Psychology, University of Queensland, Brisbane, Australia
3Australian Research Council Centre of Excellence for Integrative Brain Function, Australia
4Department of Psychology, University of Birmingham, UK
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M.I. Garrido
1Queensland Brain Institute, University of Queensland, Brisbane, Australia
3Australian Research Council Centre of Excellence for Integrative Brain Function, Australia
5School of Mathematics and Physics, University of Queensland, Brisbane, Australia
6Centre for Advanced Imaging, University of Queensland, Brisbane, Australia
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P.E. Dux
2School of Psychology, University of Queensland, Brisbane, Australia
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Abstract

Humans show striking limitations in information processing when multitasking, yet can modify these limits with practice. Such limitations have been attributed to the capacity of a frontal-parietal network, but recent models of decision-making implicate a striatal-cortical network. We adjudicated these accounts by implementing a dynamic causal modelling (DCM) analysis of a functional magnetic resonance imaging (fMRI) dataset, where 100 participants completed a multitasking paradigm in the scanner, before and after engaging in a multitasking (N=50) or an active control (N=50) practice regimen. We observed that multitasking costs, and their practice related remediation, are best explained by modulations in information transfer between the striatum and the cortical areas that represent stimulus-response mappings. Neither multitasking nor practice modulated direct frontal-parietal connectivity. Our results support the view that limits in cognitive capacity are striatally driven, and moderated by the interplay of information exchange from the putamen to the pre-supplementary motor area.

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Posted March 01, 2019.
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Cognitive capacity limits are remediated by practice-induced plasticity in a striatal-cortical network
K.G. Garner, M.I. Garrido, P.E. Dux
bioRxiv 564450; doi: https://doi.org/10.1101/564450
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Cognitive capacity limits are remediated by practice-induced plasticity in a striatal-cortical network
K.G. Garner, M.I. Garrido, P.E. Dux
bioRxiv 564450; doi: https://doi.org/10.1101/564450

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