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Functional arrays of human pluripotent stem cell-derived cardiac microtissues

Nimalan Thavandiran, Christopher Hale, Patrick Blit, Mark L. Sandberg, Michele E. McElvain, Mark Gagliardi, Bo Sun, Alec Witty, George Graham, May Mcintosh, Mohsen A. Bakooshli, Hon Le, Joel Ostblom, Samuel McEwen, Erik Chau, Andrew Prowse, Ian Fernandes, Penney M. Gilbert, Gordon Keller, Philip Tagari, Han Xu, Milica Radisic, Peter W. Zandstra, Dana Nojima, Hugo Vargas, Yusheng Qu, Alykhan Motani, Jeff Reagan
doi: https://doi.org/10.1101/566059

Article Information

doi 
https://doi.org/10.1101/566059
History 
  • March 5, 2019.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Nimalan Thavandiran1,2,
  2. Christopher Hale3,
  3. Patrick Blit4,
  4. Mark L. Sandberg5,
  5. Michele E. McElvain5,
  6. Mark Gagliardi6,
  7. Bo Sun6,
  8. Alec Witty6,
  9. George Graham4,
  10. May Mcintosh4,
  11. Mohsen A. Bakooshli1,
  12. Hon Le3,
  13. Joel Ostblom1,
  14. Samuel McEwen1,
  15. Erik Chau7,
  16. Andrew Prowse4,
  17. Ian Fernandes6,
  18. Penney M. Gilbert1,8,9,10,
  19. Gordon Keller6,
  20. Philip Tagari3,
  21. Han Xu5,*,
  22. Milica Radisic1,2,11,*,
  23. Peter W. Zandstra1,4,10,12,*,
  24. Dana Nojima13,
  25. Hugo Vargas3,
  26. Yusheng Qu3,
  27. Alykhan Motani3 and
  28. Jeff Reagan3
  1. 1Institute for Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
  2. 2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.
  3. 3Amgen Discovery Research, Amgen Inc. South San Francisco, CA, USA.
  4. 4CCRM, Toronto, Ontario, Canada
  5. 5A2 Biotherapeutics Inc. Agoura Hills, CA USA
  6. 6McEwen Centre for Regenerative Medicine, University Health Network, Toronto, Ontario, Canada.
  7. 7Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
  8. 8Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
  9. 9Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada
  10. 10Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.
  11. 11Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario, Canada.
  12. 12Michael Smith Laboratories, School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada.
  13. 13Merck Research, 630 Gateway Blvd., South San Francisco, CA, USA
  1. ↵*Corresponding authors
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Posted March 05, 2019.
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Functional arrays of human pluripotent stem cell-derived cardiac microtissues
Nimalan Thavandiran, Christopher Hale, Patrick Blit, Mark L. Sandberg, Michele E. McElvain, Mark Gagliardi, Bo Sun, Alec Witty, George Graham, May Mcintosh, Mohsen A. Bakooshli, Hon Le, Joel Ostblom, Samuel McEwen, Erik Chau, Andrew Prowse, Ian Fernandes, Penney M. Gilbert, Gordon Keller, Philip Tagari, Han Xu, Milica Radisic, Peter W. Zandstra, Dana Nojima, Hugo Vargas, Yusheng Qu, Alykhan Motani, Jeff Reagan
bioRxiv 566059; doi: https://doi.org/10.1101/566059
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